Hypocalcemia and resistance to exogenous parathyroid hormone have been reported in several clinical states associated with magnesium deficiency. On the basis of such observations, it has been suggested that magnesium depletion per se may result in impaired responsiveness of the adenyl cyclase-adenosine 3',5'-monophosphate (3',5'-AMP) system. To test this hypothesis, 4 wk old male parathyroidect...

Introduction Phaeochromocytoma may occasionally induce hypercalcaemia. Case reports of correction of hypercalcaemia by surgical removal of the phaeochromocytoma indicate the importance of humoral mechanisms (Swinton, Clerkin and Flint, 1972; Kukreja et al., 1973). Kukreja et al. (1973) noted a pre-operative elevation of serum immuno-reactive parathyroid hormone (i-PTH) implying that hypercalcae...

Recent evidence links osteoporosis, a disease of bone remodeling, to changes in the dynamics of parathyroid hormone secretion. We use nonlinear and linear time series prediction to characterize the secretory dynamics of parathyroid hormone in both healthy human subjects and patients with osteoporosis. Osteoporotic patients appear to lack the periods of high predictability found in normal humans...

the role of parathyroid hormone on stature in major beta-thalassemic patients   gr. moshtaghi kashanian phd 1 , a. ahmadi md2, mm. hayat bakhsh md3   1- assistant professor, dept. of biochemistry, faculty of medicine, university of medical sciences, kerman, iran   2- professor of pediaterics, university of medical sciences, kerman, iran   3- assistant professor of internal medicine, faculty of ...

The role of the parathyroid hormone in the regulation of calcium and phosphate metabolism has been recognized for many years (1). At the cellular level, the hormone is thought to regulate calcium and phosphate transport reactions. It is now known to (a) increase calcium reabsorption in the renal tubule (2, 3), (b) increase the transport of calcium across intestinal membranes (a, 5), (c) increas...

  Introduction: Radio-guided parathyroid surgery along with other minimally invasive surgeries constitutes the main surgical treatment procedures for different kinds of hyperparathyroidism.  In this article we have reported our experience of radio-guided parathyroid surgery using Tc-99m sestamibi. Methods: Ten patients with hyperparathyroidism included in our study. ...

An 8-15S fraction of RNA isolated from hyperplastic human parathyroid tissue (primary chief-cell hyperplasia) and translated in a cell-free extract of wheat germ directs the synthesis of a protein that shares antigenic determinants and tryptic peptides with parathyroid hormone and its previously recognized immediated precursor, proparathyroid hormone. In addition, the protein contains tryptic p...