background: eukaryotic proteins generally have signal peptides, which are not only crucial for their secretion efficiencies but are important for their expression levels. the coagulation factor ix (fix) is a glycoprotein that plays a fundamental role in a blood coagulation pathway. reduced levels or dysfunctional fix are associated with hemophilia b. to improve the hfix secretion efficiency in ...

two hundred and fifty-eight iranian university students estimated their own, parents', and partners' overall (general) intelligence, and also estimated 13 'multiple intelligences' on a simple, two-page questionnaire which was previously used in many similar studies. in accordance with previous research, men rated themselves higher than women on logical-mathematical, spatial and musical intellig...

The aim of this study was to examine individual differences in a large sample of complete melatonin profiles not suppressed by light and search for possible associations between the amount and timing of melatonin secretion and a multitude of lifestyle variables. The melatonin profiles were derived from saliva samples collected every 30 minutes in dim light from 85 healthy women and 85 healthy m...

The purpose of this research is the development of a robot partner system based on modular cognitive model for human support. In order to implement information support of daily life to human, smooth human–robot interaction is needed. The interaction with a robot partner requires many elements including verbal communication, non-verbal communication, and embodiment as well. These modular structu...

Two-partner secretion (TPS) systems are a family of proteins being rapidly identified and characterized in a growing number of gram-negative bacteria. TPS systems mediate the secretion of proteins, many involved in virulence traits such as hemolysis, adherence to epithelial cells, inhibition of bacterial growth, and immunomodulation of the host. A TPS system typically consists of a transporter ...

The two-partner secretion (TPS) pathway is widespread among gram-negative bacteria and facilitates the secretion of very large and often virulence-related proteins. TPS systems consist of a secreted TpsA protein and a TpsB protein involved in TpsA transport across the outer membrane. Sequenced Neisseria meningitidis genomes contain up to five TpsA- and two TpsB-encoding genes. Here, we investig...