Schiff bases are the most widely used organic compounds in which the carbonyl group is replaced by an imine or azomethine group. These compounds are very important in medicinal and pharmaceutical fields because of their wide spectrum. Most of them show biological activities such as antimicrobial and antifungal activity. This review summarizes the synthesis and antimicrobial activities of Schiff...

The Ocean, which is called the "mother of origin of life," is also the source of structurally unique natural products that are mainly accumulated in living organisms. Cyanobacteria are photosynthetic prokaryotes used as food by humans. They are excellent source of vitamins and proteins vital for life. Several of these compounds show pharmacological activities and are helpful for the invention a...

Background & Aims of the Study: Pharmaceutical compounds have a variety of forms and applications. Specific amounts of toxic organic compounds in the process of their manufacturing and utilization cause environmental pollution problems. So, degradation and removal these compounds are necessary. The aim of this paper is the study photocatalytic degradation of ciprofloxacin drug in aqueous soluti...

We describe the synthesis and screening of a DNA-encoded chemical library containing 76230 compounds. In this library, sets of amines and carboxylic acids are directly linked producing encoded compounds with compact structures and drug-like properties. Affinity screening of this library yielded inhibitors of the potential pharmaceutical target tankyrase 1, a poly(ADP-ribose) polymerase. These c...

3-Methoxybenzamide (1) is a weak inhibitor of the essential bacterial cell division protein FtsZ. Alkyl derivatives of 1 are potent antistaphylococcal compounds with suboptimal drug-like properties. Exploration of the structure-activity relationships of analogues of these inhibitors led to the identification of potent antistaphylococcal compounds with improved pharmaceutical properties.

In pharmaceutical bioanalysis, researchers develop and run various assays to quantitate drugs, pharmaceutical candidates, and their metabolites in biological fluids such as serum and plasma. The data resulting from these assays are used to help determine the pharmacodynamic and pharmacokinetic properties as well as the toxic and therapeutic concentrations of existing and emerging pharmaceutical...

With the increasing interest in polymers of natural origin, the pharmaceutical world has compliance to use most of them in their formulations. Moreover, the tremendous orientation of pharma world towards these naturally derived polymers has become a subject of increasing interest to discover, extract and purify such compounds from the reported origin. In the present review we have discussed muc...

background and objectives: many members of the amaryllidaceae are regarded as toxic. the toxic constituents that occur in the whole family are referred to as the amaryllidaceae alkaloids. the main aim of this study was the identification of alkaloid compounds from galanthus transcaucasicus fomin, a medicinal plant from amaryllidaceae. methods: planar and column chromatography techniques were us...