Escherichia coli Era is a GTP binding protein and essential for cell growth. We have previously reported that an Era mutant, designated Era-dE, causes a dominant negative effect on the growth and the loss of the ability to utilize TCA cycle metabolites as carbon source when overproduced. To investigate the role of Era, the gene expression in the cells overproducing Era-dE was examined by DNA mi...

Juvenile idiopathic arthritis (JIA) is a chronic, inflammatory disease of unknown etiology. The enthesitis-related arthritis (ERA) JIA category describes a clinically heterogeneous group of children including some who have predominately enthesitis, enthesitis and arthritis, juvenile ankylosing spondylitis, or inflammatory bowel disease-associated arthropathy. ERA accounts for 10%-20% of JIA. Co...

The presence of calcium and humic substances or natural organic matter (NOM) in surface waters can cause severe fouling of nanofiltration (NF) membranes. Conditions of fouling were studied using a stainless steel stirred cell of volume 185 mL and a membrane area of 21.2*10-4m2 at a transmembrane pressure of 5 bar. Deposition of organic matter was determined by mass balance in feed and concentra...

BACKGROUND Organ transplantation has proven highly effective in the treatment of various forms of end-stage organ failure. However, organ shortage is still the greatest challenge facing the field of organ transplantation. OBJECTIVE To assess the pattern of organ donation and utilization during the past decade in the USA. METHODS We studied OPTN/UNOS database for organ donation between Janua...

Era (E. coliRas-like protein) is a highly conserved and essential GTPase in bacteria. It binds to the 16S ribosomal RNA (rRNA) of the small (30S) ribosomal subunit, and its depletion leads to accumulation of an unprocessed precursor of the 16S rRNA. We have obtained a three-dimensional cryo-electron microscopic map of the Thermus thermophilus 30S-Era complex. Era binds in the cleft between the ...

several factors influenced on the presence of women in the pahlavi era. in the new structures after the constitutionalism and along with modernism of pahlavi, court became to the government and political figures changed to the people. in this era, the role of women in sexual approach, their changed from a class-in-itself to class-for-itself. the outgrowth of social backdrops caused that we can ...

We conducted a synthesis analysis on data from 86 published field experiments conducted from 1903 to 2014 to explore the specific consequences of post-silking N accumulation (PostN) in New Era vs. Old Era hybrids on grain yield (GY) and recovery from plant N stress at flowering (R1 stage). The Old Era encompassed studies using genotypes released before, and including, 1990 and the New Era inclu...

PURPOSE To evaluate the survival of patients with human epidermal growth factor receptor 2 (HER2) positive and negative metastatic breast cancer irradiated for brain metastases before and after the availability of trastuzumab (T). MATERIALS AND METHODS Women diagnosed with brain metastasis from breast cancer in two eras between 2000 and 2007 (T-era, n = 441) and 1986 to 1992 (PreT-era, n = 30...

Results The median age overall was 17.1(13-21) years. 28.9% (46) of individuals had ERA, of which 69.6% (39) were male. Mean duration of disease since diagnosis was 7.3 years (SD=+/-4.9). Of the other JIA subtypes; 21.4% (34), 17.6% (28) and 11.9% (19) had Extended Oligoarticular Arthritis (EOA), Polyarticular Rheumatoid Factor Positive (JIA RF+) and Polyarticular Rheumatoid Factor Negative (JI...