Both the oxidation product of a-tocopherol, ol-tocopherylquinone, and the reduction product of the latter, a-tocopherylhydroquinone (I), have been shown to possess vitamin E activity in preventing or curing nutritional muscular dystrophy in the rabbit (1). Whiie the quinone is far more stable than the hydroquinone (I), its antidystrophic activity is of a lower order. Since I, however, is extrem...

les composes organophosphores en general et les esters phosphoriques en particulier, suscitent un interet, sans cesse grandissant , qui peut se justifier par l'importance de ces produits (nucleotides, phospholipides, etc.) dans les processus biologique. dans ce mernoire nous presentons les etudes des polyesters phosphoriques surtout sur le plan purement chimique. apres avoir mentionne les ...

Alkyl esters of pectin and pectic acid have been prepared via three different synthetic routes. Enhancements of intrinsic viscosity, binding to bile acids and to isolated soy protein were shown for these novel pectin derivatives. The development of new and improved pectin-containing products may be enhanced by the ease of preparation and improved functionality of such compounds.

The amount of active groups of cyanate esters and imidocarbamates present on cyanogen-bromide-activated paper discs were estimated. The protein-binding capacity of activated discs was found to be dependent on the amount of these active groups. The results suggested that monitoring of active groups on activated discs can help in preparing consistent allergosorbent for immunoassays.

The efforts for synthesis of enantiomerically pure bis-(1,2,3-triazolylmethyl)amino esters 6 are reported in good yields from an in situ generated α-azidomethyl ketone. Optimum experimental conditions were established for preparation of α-halomethyl ketones 10 and α-N,N-dipropargylamino esters 11, all derived from α-amino acids. The starting materials reacted under conventional click chemistry ...

The phosphotriesterase from Pseudomonas diminuta has been shown to selectively cleave the pro-R p-nitrophenolate substituent from bis-p-nitrophenyl alkyl phosphothioate esters. When the alkyl substituent is methyl, ethyl, or isopropyl the enantiomeric excess of the product is >/=99%. Manipulation of the active site through mutagenesis has enabled the preparation of protein variants that prefere...

Theoretical insights elucidate a series of active phosphonate esters application in preparation of Cephalosporin antibiotics’ intermediate. The B3LYP/6-311+G(d,p) method was employed to obtain the stable equilibrium geometries including comparing to the AE-active ester. It was found that the Ethyl-aminothiazoly Loximate (AT) molecule fragment is almost planar sheet, but it is almost perpendicul...