The utilization of TiB2 particles reinforced aluminum (Al6063) metal matrix composite materials in many different engineering fields has undergone a tremendous increase. Accordingly, the need of accurate machining of composites has increased enormously; an attempt has been made to assess the factors influencing surface roughness and material removal rate on machining the composite. The orthogon...

We show that chemical fixation enables top-down micro-machining of large periodic 3D arrays of protein-encapsulated magnetic nanoparticles (NPs) without loss of order. We machined 3D micro-cubes containing a superlattice of NPs by means of focused ion beam etching, integrated an individual micro-cube to a thin-film coplanar waveguide and measured the resonant microwave response. Our work repres...

objective(s): the oct4b1, as one of oct4 variants, is expressed in cancer cell lines and tissues more than other variants and plays an important role in apoptosis and stress (heat shock protein) pathways. the present study was designed to determine the effects of oct4b1 silencing on expressional profile of hsp40 gene family expression in three different human tumor cell lines. materials and met...

Here, the first cDNA array analysis of differential gene expression in bovine spongiform encephalopathy (BSE) is reported, using a spotted cDNA array platform representing nearly 17 000 mouse genes. Array analysis identified 296 gene candidates for differential expression in brain tissue from VM mice in late-stage infection with the 301V strain of BSE, compared with brain tissue from normal, ag...

Protein profiling and characterization of protein interactions in biological samples ultimately require indicator-free methods of signal detection, which likewise offer an opportunity to distinguish specific interactions from nonspecific protein binding. Here we describe a new 3-dimensional protein microchip for detecting biomolecular interactions with matrix-assisted laser desorption-ionizatio...

Summary Relational arrays represent measures of association between pairs actors, often in varied contexts or over time. Trade flows countries, financial transactions individuals, contact frequencies school children classrooms and dynamic protein-protein interactions are all examples relational arrays. Elements a array modelled as linear function observable covariates. Uncertainty estimates for...