Many tumor tissues are made up of genetically different cell populations, and the study of the causes and consequences of this heterogeneity must play a central role in cancer research. We have studied breast cancer clonal heterogeneity by cytogenetic analysis of 4123 cells from 52 successfully short-term-cultured tumorous, metastatic, and macroscopically normal breast tissue samples from 6 wom...

G-banded chromosomes were studied from involved lymph nodes or other tumor masses in 94 patients with malignant lymphoma. Clonal chromosome abnormalities were identified in 91 patients including all 81 B-lymphomas but only 6 of 9 Tlymphomas. Many recurring chromosome abnormalities were found. Most common numerical alterations involved gains of chromosomes 12 (19% of patients), 18 (13%), 7 (12%)...

The pollucite structure is considered as a candidate ceramic crystalline matrix for the immobilization and long-term storage of 135Cs 137Cs fission products, thus, their structural characteristics have particular importance. However, its local has not been fully resolved from reciprocal-space techniques infrared spectroscopy, important discrepancies exist in available literature. Two birefringe...

The development of the electricity sector in Albania continues to be fenced by high rates inefficiencies, insufficient security supply, low rate RES investment including wind power plants and need further unbundle liberalise energy market following adoption legal basis, GHG credits is inevitable. A lot issues are set face challenges transition, oriented Albanian government’s endeavor maintain a...

The membrane-bound ATP synthase (F(1)F(o)) from mitochondria, chloroplasts and bacteria plays a crucial role in energy-transducing reactions. In the case of Escherichia coli, the reversible, proton-translocating ATPase complex consists of two different entities, F(1) and F(o). The water-soluble F(1) part carries the catalytic sites for ATP synthesis and hydrolysis. It is associated with the mem...

Introduction aCGH determines pathogenic copy number variations (CNVs) in about 10% of patients with intellectual disability (ID). In another 20% patients, probably CNVs or variants uncertain clinical significance are detected. It may be that do not fully explain the patient’s symptoms, aberrations reduced penetrance inherited from healthy parents. The use a sequencing method for such cases is a...