in this article, a finite horizon, multi product and multi period economic order quantity like seasonal items is considered where demand rate is deterministic and known but variable in each period. the order quantities of items come in batch sizes and the end of the period order quantity and, consequently, demand of customers are zero. in addition, storage space is constrained and the problem ...

there are many benefits for coordination of multiple suppliers when single supplier cannot satisfy buyer demands.  in addition, buyer needs to purchase multiple items in a real supply chain. so, a model that satisfies these requests has many advantages. we extend the existing approaches in the literature that assume all suppliers need to be put on a common replenishment cycle and each supplier ...

one main group of a transportation network is a discrete hub covering problem that seeks to minimize the total transportation cost. this paper presents a multi-product and multi-mode hub covering model, in which the transportation time depends on travelling mode between each pair of hubs. indeed, the nature of products is considered different and hub capacity constraint is also applied. due to ...

BACKGROUND Hypothermia prolongs the time course of action of nondepolarizing muscle relaxants. It is not known whether this prolongation is caused by a reduced rate of extrahepatic distribution or elimination, liver uptake, metabolic clearance, or biliary excretion. Therefore, the authors studied the effects of hypothermia on the net hepatic uptake, metabolism, and biliary excretion of vecuroni...

a multi objective honey bee mating optimization (hbmo) designed by online learning mechanism is proposed in this paper to optimize the double fuzzy-lead-lag (fll) stabilizer parameters in order to improve low-frequency oscillations in a multi machine power system. the proposed double fll stabilizer consists of a low pass filter and two fuzzy logic controllers whose parameters can be set by the ...

an integrated model considers all parameters and elements of different deficiencies in one problem. this paper presents a new integrated model of a supply chain that simultaneously considers facility location, vehicle routing and inventory control problems as well as their interactions in one problem, called location-routing-inventory (lri) problem. this model also considers stochastic demands ...

the emergence of multi-drug resistant strains of pseudomonas aeruginosa has complicated treatment decision and may lead to treatment failures. in this study, we describe the trends of drug-resistant p. aeruginosa isolated in blood cultures from patients detected in a tertiary teaching hospital and evaluated the prevalence of resistance to amikacin, ampicillin, carbeni- cillin, cefixime, cefotax...

rayleigh-taylor (rt) instability has a growing importance in many fields including aircraft industry and astrophysics. the development and the growth of rt instability were investigated using sinusoidal disturbances with different wavelength at the interface of two fluids. numerical simulations were performed by solving navier-stokes unsteady equations with the vof formulation. results of the 2...