Malignant pleural mesothelioma (MPM) is a rapidly fatal malignancy that is increasing in incidence in Japan. In this study, we performed gene and microRNA (miRNA) expression profiling to identify novel therapeutic targets in MPM cells. Based on relative sensitivities to pemetrexed (PEM) and the histone deacetylase (HDAC) inhibitor, vorinostat (SAHA), 211H cells were determined to be the only se...

Recombinant wild-type human serum albumin (rHSA), the single-residue mutants R410A, Y411A, Y411S and Y411F and the double mutant R410A/Y411A were produced using a yeast expression system. The recombinant proteins were correctly folded, as they had the same stability towards guanidine hydrochloride and the same CD spectrum as HSA isolated from serum (native HSA). Thus the global structures of th...

BACKGROUND It is reported that up to one-third of patients might have some postoperative complications after percutaneous nephrolithotomy (PCNL). The predictive factors for infectious and major complications remains conflicted, which was the main objective of this study. METHODS This was a retrospective analysis using data from enrolled 411 patients diagnosed with renal stones underwent PCNL ...

[Cheney P: Fatal human plague-Arizona and Colorado, 1996. Ann Emerg Med March 1998;31:410-411.].

[This corrects the article on p. 411 in vol. 26, PMID: 24966650.].

Edwin Bernbaum, Sacred Mountains of the World (Cambridge: Cambridge University Press, 2nd ed, 2022), 411 pp., $29.99 (pbk), ISBN:9781108-8334742.