نتایج جستجو برای: resistance gene
تعداد نتایج: 1451386 فیلتر نتایج به سال:
Background and purpose: Staphylococcus aureus is one of the most common nosocomial pathogens especially among burn patients. Aminoglycoside is usually used in combination with other antibiotics for treatment of serious S. aureus infections. Resistance to aminoglycoside antibiotics is one of the most important problems in treatment of S.aureus infections. The aim of the present study was to dete...
background and objectives: macrolide, lincosamide and streptogramin type b (mlsb) antibiotics are important in the treatment of staphylococcus aureus infections and existence of isolates with ability to resist against mlsb antibiotics is worrisome. materials and methods: in this cross sectional study, 101 s. aureus isolates were collected from patients of five selected hospitals in tehran over ...
Objective(s): Regarding the global burden of uropathogenic Escherichia coli (UPEC) infections, prevention and treatment of such infections play a significant role in healthcare management. The inordinate use of fluoroquinolones led to a worldwide spread of quinolone-resistant strains. Therefore, this study aimed to investigate mutations in codons 83 and 106 of gyrA gene in UPEC isolates in the ...
Introduction & Objective: Enterococci have emerged as the leading nosocomial pathogens. In addition to natural resistance to many agents, enterococci have also developed plasmid- and transposon-mediated resistance to high concentrations of aminoglycosides. High-level gentamicin resistance (HLGR) of enterococci results in the failure of drug synergism with an aminoglycoside plus cell-wall-acti...
Background & Aims: Nowadays, the common use of azoles has led to increased resistance to azole among Candida albicans strains. Amino acid substitutions in azole target enzyme, ERG11p, is attributed to azole resistance in some clinical strains of Candida albicans. The aim of this study was to evaluate ERG11 gene mutations in fluconazole-resistant isolates of Candida albicans in Rasht. Materials...
Introduction: Acinetobacter baumannii is an important bacteria because of high ability to obtain antibiotic resistance genes and creation of multi-drug resistant strains (MDR). Today, the active efflux pumps has been suggested as one of the most important mechanisms of intrinsic and acquired resistance of antibiotics in bacteria. The aim of this study was Evaluation of phenotypic and genotypic ...
fusarium head blight (fhb) caused by fusarium graminearum is a serious disease of wheat (triticum aestivum l.), through which grain quality losses are induced by fungal trichotecene mycotoxins such as deoxynivalenol (don). a class of plasma membrane localized abc transporter proteins related to the yeast pdr5 (pleiotropic drug resistance5) efflux pump seems to be responsible for partial resista...
conclusions the results of this study indicated that a decrease in oprd gene expression is an important mechanism of resistance in carbapenem resistant pseudomonas aeruginosa isolated from severe burn patients with secondary infection. results our study showed that 94.2% of the isolates were resistant to imipenem, 99.5% to meropenem, and all were resistant to ertapenem. the oprd gene expression...
Fusarium head blight (FHB) caused by Fusarium graminearum is a serious disease of wheat (Triticum aestivum L.), through which grain quality losses are induced by fungal trichotecene mycotoxins such as deoxynivalenol (DON). A class of plasma membrane localized ABC transporter proteins related to the yeast PDR5 (pleiotropic drug resistance5) efflux pump seems to be responsible for partial resista...
Background: Clindamycin is a suitable antibiotic for treatment of skin and soft tissue infections. Moreover, it can suppress toxin production in many pathogenic bacteria such as S. aureus. There are two mechanisms of resistance in this antibiotic. Constitutive resistance can be detected by standard disk diffusion method but in the case of inducible resistance, D-test should be carried out. The ...
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