The propagation of bend and shear waves through an elastic rod is investigated in the framework of geometrically exact nonlinear elasticity. The model allows for shear, extension/compression, bend and twist thus enabling the study of the dynamics of all types of elastic deformations. Numerical and analytical solutions demonstrate that the propagation of planar bend or shear disturbances of fini...

Transdermal enhancement effects of electroporation applied only on the stratum corneum by two electrode types, the stamp-type electrode and the frog-type electrode, were investigated in vitro using excised rat skin. Carboxyfluorescein (CF) was selected as a model compound. The excised skin was set in a Franz type diffusion cell and a square wave electric pulse was applied to the stratum corneum...

In cat retina, rod bipolar terminials do not synapse on ganglion cells but on two types of amacrine cell (types I and II). Cone bipolars synapse directly on ganglion cells and on type I amacrines. The type II amacrine appears to play a special internuncial role between bipolars and ganglion cells in the rod system.

Mice carrying a targeted disruption of the rhodopsin gene develop a severe degenerative retinopathy, failing to elaborate rod photoreceptor outer segments (ROS), having no recordable rod electroretinogram (ERG) and losing all of their rod cells over a period of approximately 12 weeks. Murine and human rhodopsins differ in their amino acid sequences. Whether, or to what extent, such variability ...

Because the mouse retina has become an important model system, we have begun to identify its specific neuron types and their synaptic connections. Here, based on electron micrographs of serial sections, we report that the wild-type mouse retina expresses the standard rod pathways known in other mammals: (1) rod --> cone (via gap junctions) to inject rod signals into the cone bipolar circuit; an...

A rectangular rod is placed in a flow field flowing parallel to a flat plate. Effect of chord-thickness ratio of rectangular rod on developing vortex shedding downstream to the rod is studied. Then, for each one of the aspect ratios, the distance of the rod from the neighboring flat plate is reduced until the rod sticks to the flat plate. In each case, the effect of the flat plate boundary laye...

Mutations in rhodopsin, the light-sensitive protein of rod cells, are the most common cause of autosomal dominant retinitis pigmentosa (ADRP). Many rod opsin mutations, such as P23H, lead to misfolding of rod opsin with detrimental effects on photoreceptor function and viability. Misfolded P23H rod opsin and other mutations in the intradiscal domain are characterized by the formation of an inco...

Gas spark switches had been applied extensively in the field of pulse power technology on account advantages a simple structure, short breakdown time, and high through-current capability. This paper investigates streamer process two-electrode switch nitrogen environment under atmospheric pressure using numerical method. First, two-dimensional fluid simulation was carried out for generated negat...