The provenance of a data product contains information about how the product was derived, and is crucial for enabling scientists to easily understand, reproduce, and verify scientific results. Currently, most provenance models are designed to capture the provenance related to a single run, and mostly executed by a single user. However, a scientific discovery is often the result of methodical exe...

Is innovation primarily determined by scientific constraints and motivated by past scientific discoveries? Or does innovation respond to profit incentives? In this paper, we develop a simple model linking innovation to potential market size, and show that under a variety of circumstances, a greater market size for a particular product, which implies greater profitability from sales, spurs faste...

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Recently, WHO, EU, Japan and Canada have published guidelines on biosimilar/follow-on biologics. While there seems to be no significant difference in the general concept in these guidelines, the data to be submitted for product approval are partially different. Differences have been noted in the requirements for comparability studies on stability, prerequisites for reference product, or for the...

Do intellectual property (IP) rights on existing technologies hinder subsequent innovation? Using newly-collected data on the sequencing of the human genome by the public Human Genome Project and the private firm Celera, this paper estimates the impact of Celera's gene-level IP on subsequent scientific research and product development. Genes initially sequenced by Celera were held with IP for u...

Large-scale scientific workflows can perform many computationally intensive tasks and generate large volumes of derived data products. These systems pose many challenges to both creating and managing data products, including efficiently executing tasks and tracking data product lineage and metadata. In this paper we describe our experiences implementing an experimental data-product management s...

This paper presents empirical evidence on the effects of external knowledge sourcing strategies on the development of both product and process innovations, and assesses the degree to which such effects are influenced by the firm’s internal technological capacities. In our analysis, we consider two strategies for acquiring external knowledge (buying and cooperating) and two types of external sou...

BACKGROUND The product quality of curry is determined by the food animal source, raw materials and the method of processing. Moreover the scientific information on processing and quality of traditional buffalo meat curry from different groups of buffaloes is not available. This study was undertaken to develop processed curry from different buffalo groups and to compare its quality during storag...

The mission to make humans less attractive to mosquitoes has fuelled decades of scientific research on mosquito behaviour and control. The search for the perfect topical insect repellent/killer continues. This analysis was conducted to review and explore the scientific information on toxicity produced by the ingredients/contents of a herbal product. In this process of systemic review the follow...