This paper describes a simple microfluidic sorting system that can perform size-profiling and continuous mass-dependent separation of particles through combined use of gravity (1g) and hydrodynamic flows capable of rapidly amplifying sedimentation-based separation between particles. Operation of the device relies on two microfluidic transport processes: i) initial hydrodynamic focusing of parti...

We present a miniaturized CMOS impedance detector integrated within a dielectrophoretic microfluidic device for label-free separation, enabling the sorting and counting of particle suspensions in a fully electrical manner. This approach makes possible a truly portable system for cell sorting and analysis. Towards this end, the design of ad hoc coplanar electrodes for impedance sensing, supporte...

In this paper, initial processing of biological material, cell separation algorithms and other procedures are discussed. For samples with initial infiltration of plasma cells > 5%, CD138 MicroBeads and Auto-Magnetic-Activated Cell Sorting program are used. Fluorescence-Activated Cell Sorting is used exclusively for cell populations with low-abundance; these samples are detected using fluorescen...

Abstract Deinterleaving or radar pulse separation is a very important goal in terms of sources for identifying and implementing electronic warfare systems. In order to separate pulses, parameters measured by receivers such as support measures (ESM) signals intelligence (ELINT) are used separation. This paper presents multi-parameter improved method separating the sequence based on time arrival ...

In this study, we report on the development of the first membrane-less, clog-free microfiltration platform for ultra-high throughput (up to 1000 mL/min) cell separation, using a massively-multiplexed array of inertial microfluidic cell sorting channels. Our developed system consists of multiple layer (10~20) of PDMS sheets with embossed microchannels (i.e., ~ 200 individual spirals) bonded toge...

the objective of this research was to develop a suitable method for color sorting of fruits. accordingly, a color-sorting system was designed and a prototype developed and then tested. this system includes an optic head which is designed to develop a reflection of the fruit. output of the head is then processed in an electronic control system which generates the appropriate signal for ejection ...

Neural stem cells are of special interest due to their potential in neurogenesis to treat spinal cord injuries and other nervous disorders. Flow cytometry, a common technique used for cell sorting, is limited due to the lack of antigens and labels that are specific enough to stem cells of interest. Dielectrophoresis (DEP) is a label-free separation technique that has been recently demonstrated ...

We propose a general and scalable approach to isotope separation. The method is based on an irreversible change of the mass-to-magnetic moment ratio of a particular isotope in an atomic beam, followed by a magnetic multipole whose gradients deflect and guide the atoms. The underlying mechanism is a reduction of the entropy of the beam by the information of a single scattered photon for each ato...

Background and Objectives: The inability of classic fluorescence-activated cell sorting to single cancer cell sorting is one of the most significant drawbacks of this method. The sorting of cancer cells in microdroplets significantly influences our ability to analyze cancer cell proteins. Material and Methods: We adapted a developed microfluidic device as a 3D in vitro model to sorted MCF-7 c...

In Xenopus laevis, patterning of the trunk mesoderm into the dorsal notochord and lateral somites depends on differential regulation of Wnt-beta-catenin signaling. To study the cellular requirements for the physical separation of these tissues, we manipulated beta-catenin activity in individual cells that were scattered within the trunk mesoderm. We found that high activity led to efficient cel...