microdialysis was used to measure the effect of benzodiazepines (bdzs) on basal levels and on stress-induced increases of 5 -hydroxytryptamine (5 -ht), 5 - hydroxyind oleacetic acid (5 -hiaa) , noradrenaline (na), and dihydroxyphenylacetic acid (dop ac). the stressors used were a 5 min tail pinch or a 10 min period of restraint. a subcutaneous injection of 5 mg/kg diazepam decreased basal level...

background: the interaction between serum neuron-specific enolase (nse), biogenic amino-acids and neurobehavioral function with blood lead levels in workers exposed to lead form lead-acid battery manufacturing process was not studied. objective: to evaluate serum nse and biogenic amino-acids (dopamine and serotonin) levels, and neurobehavioral performance among workers exposed to lead from lead...

prenatal stress in rats results in structural, physiological and behavioral alterations that persist in adulthood. serotonin (5-ht) is an important neurotransmitter known to be involved in these prenatal stress-induced behavioral alterations. the aim of the study was to investigate the effects of interrupted synthesis of 5-ht and immobilization stress during different gestational period on brai...

OBJECTIVE To determine whether use of serotonin or non-serotonin reuptake inhibitors near to delivery is associated with postpartum hemorrhage. DESIGN Cohort study. SETTING 2000-07 nationwide Medicaid data (Medicaid Analytic eXtract). POPULATION 106,000 pregnant women aged 12-55 with a diagnosis of mood or anxiety disorder. Women were categorized into four mutually exclusive exposure grou...

serotonin is believed as an important factor in brain function. the role of serotonin in cerebral psycho-patho-physiology has already been well established. however, the function of serotonin antagonist in anesthetized subjects under hyperthermia has not been studied properly. methods: experiments were performed in three groups of urethane-anesthetized rats, such as: (i) control group, (ii) who...