Objective(s): Iron is an essential element for living organisms. Iron overload can have detrimental effects on health. This study pertains to the protective role of berberine against ferrous sulfate-induced hepatic and renal functional disorders and histological damages in rats.Materials and Methods: The rats were divided into four groups (n=7): Sham, Ber (10 mg/kg/day for 14 days, by gavage), ...

Abstract Objective: Adiponectin and vaspin are adipocyte-derived proteins and involved in the regulation of glucose metabolism and obesity related disorders. The mechanisms that adipokines might be linked to disturbance of glucose are unclear. Thus, this study investigated the levels of serum adiponectin and vaspin, blood lipid profiles, and abdominal obesity in type 2 diabetes (T2DM) patients...

To assess the relative contribution of genetic and environmental factors (particularly androgens) on circulating levels of lipid fractions, serum androgen and lipid fractions were measured in 34 pairs of female-female twins aged from 15- 45 years, some of whom were discordant for polycystic ovary syndrome (PCOS) diagnosed by ultrasound. Nineteen pairs were monozygotic twins (MZ) and 15 pai...

Objective(s):The present study investigated the antidiabetic and hypolipidemic properties of Dorema aucheri leave hydroalcoholic extract in nicotinamide-streptozotocin induced type 2 diabetic rats. Materials and Methods: nicotinamide/streptozotocin-induced diabetic rats were supplemented orally with three different doses of D.  aucheri (100, 200 and 400 mg/kg BW) or glibenclamide (0.25 mg/kg) f...

because the ingestion of some types of dietary fibers has been shown to influence on the lipid and lipoprotein levels, it is possible that chitosan influences on lipid metabolism. in the present study, the effects of chitosan on the serum, liver lipid and lipoprotein concentrations in rat were investigated. serum lipid level in the treatment groups were decreased compared to that of the control...

BACKGROUND Thyroid hormones play an important role in lipid metabolism. Overt hypothyroidism is known to be associated with increased lipid profiles, but the effect of subclinical hypothyroidism (SCH) on lipid profile remains controversial. OBJECTIVES The aim of this study was to assess the association between thyroid disorders and serum lipid levels. MATERIALS AND METHODS The present study...

background: cancer has the highest disease-related mortality rate in iran. reduced activity of paraoxonase reported in patients with cancer may be due to a reduction in its antioxidant properties and a subsequent increased risk of developing cancer. we aimed to assess antioxidant and oxidative status in patients with cancer through measuring the activity of pon1 as an antioxidant enzyme and det...

background: leptin has been implicated in the differentiation and proliferation of hematopoietic cells. leukemia inhibitory factor (lif) may play an important role, along with interleukin-6 (il-6) and granulocyte colony stimulating factor (g- csf), in the regulation of early hematopoietic stem cells. the aim of the study was to evaluate serum level of leptin, lif, and il-6 in myeloid leukemia p...

objective: numerous iranian veterans who took part in iraq-iran war have developed post traumatic stress disorder (ptsd). several studies demonstrated changes in serum lipid concentrations in chronic ptsd (cptsd) patients. the purpose of this study was to assess serum lipid concentrations in soldiers with cptsd and compare it with serum lipid concentrations in patients with chronic mdd (cmdd). ...