et al. Clinical response and pharmacokinetics from a phase 1 study of an active dosing schedule of flavopiridol in relapsed chronic lymphocytic leukemia. Phase II study of flavopiridol in relapsed chronic lymphocytic leukemia demonstrating high response rates in genetically high-risk disease. a multicenter, international, phase 2 study of alvocidib for patients with fludarabine-refractory chron...

BACKGROUND One of the global targets for non-communicable diseases is to halt, by 2025, the rise in the age-standardised adult prevalence of diabetes at its 2010 levels. We aimed to estimate worldwide trends in diabetes, how likely it is for countries to achieve the global target, and how changes in prevalence, together with population growth and ageing, are affecting the number of adults with ...

BACKGROUND Morbid obesity can be a life threatening condition. The aim of our study is to assess the trend in morbid obesity in The Netherlands among children of Dutch origin since 1980, and among children of Turkish and Moroccan origin since 1997. METHODS AND FINDINGS Cross-sectional height and weight data of children of Dutch, Turkish and Moroccan origin aged 2-18 years were selected from t...

Mortality rates from non-Hodgkin lymphoma (NHL) have declined in many countries in recent decades. However, mortality estimates for Brazil indicate an increase in these rates. This study aimed to analyze NHL mortality trends for 1980-2007 in individuals 20 years and older in State capitals in Southeast Brazil. Population data were obtained from the Mortality Information System and the Health St...

Israel Cidon received the B.Sc (summa cum laude) and the D.Sc. degrees from the Technion -Israel Institute of Techno logy, Haifa, Israel, in 1980 and 1984, respectively, both in electrical engineering. From 1977 to 1980 he was a consulting Research and Development Engineer involved in the design of rnicroprocessor-based equipment. From 1980 to 1984 he was a Teaching Assistant and a Teaching Ins...