The main objective of the work is to prepare mefenamic acid loaded microspheres for sustained release using different polymers ethyl cellulose as synthetic polymer and sodium alginate as natural polymer and compare and selecting best suitable polymer among them. For preparing mefenamic acid microspheres ethyl cellulose used as synthetic polymer in solvent evaporation method and sodium alginate ...

Diclofenac sodium is an Non-steroidal anti-inflammatory drugs, having an elimination half-life of 1-2 hrs. The objective of the study is to prepare Diclofenac sodium Microbeaads using Natural Polymers in different concentrations. For this purpose calcium ions were used as cross linking agents in formulation of alginate-guar gumpectin, alginate-guar gum-lecithin and alginate-pectin-lecithin Micr...

Microporous osmotic tablet of diltiazem hydrochloride was developed for colon targeting. These prepared microporous osmotic pump tablet did not require laser drilling to deliver the drug to the specific site of action. The tablets were prepared by wet granulation method. The prepared tablets were coated with microporous semipermeable membrane and enteric polymer using conventional pan coating p...

Abstract Bronze has been used for various applications since ancient times, and therefore, its preservation is critical. However, preserving bronze challenging. The traditional inhibitor sealing method limited by toxicity effects. In this study, a benzotriazole (BTA) loaded with composite hydrogel of sodium alginate cyclic-peptide-grafted β-cyclodextrin was prepared. chemical structure the comp...

INTRODUCTION Pulsatile Drug delivery systems are gaining a lot of interest as they deliver the drug at the right site of action at the right time and in the right amount, thus providing spatial and temporal delivery and increasing patient compliance. Pulsatile Drug Delivery systems are basically time-controlled drug delivery systems in which the system controls the lag time independent of envir...

Recently, efforts have been focused on microparticles prepared with natural polymers such as alginates and chitosans. Sodium alginate in particular has been commercially applied and investigated due to its low cost and minimal processing requirements (Murata et al., 1993; Gombotz & Wee, 1998; Sezer & Akbuga, 1999a and b). The use of sodium alginate for microencapsulation has been extensively st...

The objective of this study was to formulate sodium alginate based ophthalmic mucoadhesive system of gatifloxacin and its in vitro antibacterial potential on pathogenic microorganisms, Staphylococcus aureus and Escherichia coli. Sodium carboxymethylcellulose (NaCMC) was added to the formulations to enhance the gel bioadhesion properties. The prepared formulations were evaluated for their in vit...

More than 3000 MT of Sargassum illicifolium ,annually washed-up from the Oman Sea (Sistan and Baluchestan province). , According to the estimates of the Iranian Fisheries Sciences Researchinstitiute.The brown seaweed biomass has been considered as one of the best free sources for production of sodium alginate. A key objective of this study was to determine the biochemical composition of Sargass...