Currently, no drug is effective in delaying the cognitive impairment of Alzheimer’s disease, which ranks as one top 10 causes death worldwide. Hydroxylated stilbenes are active compounds that exist fruit and herbal plants. Piceatannol (PIC) gnetol (GNT), have extra hydroxyl group comparison to resveratrol (RSV), rhapontigenin (RHA) isorhapontigenin (isoRHA), were metabolized from PIC vivo conta...