The inhibition effect of Capsella bursa-pastoris extracts (CBE) and its synergistic effect with KI (CBEK) for Q235 mild steel in 1 M HCl solution were studied by electrochemical measurements. Both CBE and CBEK can serve as eco-friendly, mixed-type inhibitors, and the inhibition efficiency increases with the concentration and temperature. The synergistic parameter (SI) indicates a cooperative me...

The use of antibacterial drug combinations with synergistic effects is increasingly seen as a critical strategy to combat multi-drug resistant bacteria such as methicillin-resistant Staphylococcus aureus (MRSA). In this work, the proteome responses in MRSA under the stress of a sub-inhibitory dose of a synergistic drug combination of a novel erythromycin derivative, SIPI-8294, and oxacillin, we...

The aim of the present study was to investigate the influence and the mechanisms of cineoleand terpineol on the in-vitro transdermal delivery of huperzine A from microemulsions, andtheir potential synergistic effect on the permeation enhancement. The transdermal deliveryof huperzine A from microemulsions with different concentrations of cineole and terpineolthrough the rat abdominal skin was de...

The aim of the present study was to investigate the influence and the mechanisms of cineoleand terpineol on the in-vitro transdermal delivery of huperzine A from microemulsions, andtheir potential synergistic effect on the permeation enhancement. The transdermal deliveryof huperzine A from microemulsions with different concentrations of cineole and terpineolthrough the rat abdominal skin was de...

Background and Objectives The antimicrobial combination with synergistic mechanism is recommended to provide broad-spectrum coverage, and prevent the emergence of resistant mutants. In the present study, the synergistic activity of lysostaphin with linezolid, oxacillin and vancomycin, against methicillin-resistant Staphylococcus aureus (MRSA) clinical isolates was determined. Materials and Me...

objective: immunotoxins (its) have been developed for the treatment of cancer, and comprise of antibodies linked to toxins. also vascular endothelial growth factor (vegf) plays a key role in tumor angiogenesis, and the blockade of vegf receptor-2 (vegfr2) inhibits angiogenesis and tumor growth. the aim of this study was to produce anti-vegfr2/rpe (pseudomonas exotoxin) 38 it to test its cytotox...

The epithelial surfaces of the upper respiratory tract are continuously exposed to a wide variety of commensal microorganisms. In addition to acting as a physical barrier, epithelial cells respond to specific microbial products with the generation of signals, such as cytokines, that trigger inflammation. Because they are common components of the nasopharyngeal flora that share the potential to ...