OBJECTIVE: Diabetes mellitus and thyroid disease are the two common endocrinopathies seen in adult population. Studies to evaluate thyroid disorders in patients with type 2 diabetes are lacking. The aim of this study was to compare prevalence of thyroid dysfunction and autoim-munity in type 2 diabetic patients with age and sex matched non-diabetic control group. MATERIAL AND METHODS: Among pat...

In 1999, 890 000 measurements of thyroid stimulating hormone were performed by Scottish hospital laboratories—approximately one test for every six of Scotland’s 5.1 million people. This number does not include tests performed in the non-NHS laboratories or as part of the screening programme for congenital hypothyroidism. Although laboratory statistics are not collected nationally in England and...

Previously we have reported that thyroid-stimulating hormone stimulates glucose-l-C4 oxidation in thyroid slices in vitro and that this effect appeared to be secondary to an increase in nicotinamide adenine dinucleotide phosphate levels in the tissue (l-3). Although the effect of thyroid-stimulating hormone on glucose oxidation in vitro was apparent within 5 minutes of its addition to the thyro...

Background and Aims: 25-hydroxy vitamin D3 is recognized to be an essential element for healthy body; however, its deficiency has been identified as a risk factor for thyroid disease, diabetes mellitus and other autoimmune diseases and infectious diseases. Thyroid disease is common in the general population that its prevalence increases proportional to age. Subjects with poorly controlled diabe...

PURPOSE Premature ejaculation is considered the most common type of male sexual dysfunction. Hormonal controls of ejaculation have not been exactly elucidated. The aim of our study is to investigate the role of hormonal factors in patients with premature ejaculation. MATERIALS AND METHODS Sixty-three participants who consulted our outpatient clinics with complaints of premature ejaculation an...

BACKGROUND Environmental exposure of infants to perchlorate, thiocyanate, nitrate, might interfere with thyroid function. U.S. women with higher background perchlorate exposure have higher thyroid-stimulating hormone (TSH) and lower thyroxine (T4). There are no studies with individual measures of thyroid function and these goitrogens available in infants. OBJECTIVE We examined the association...

Dear Editor, Resistance to thyroid hormone (RTH) is a syndrome of reduced responsiveness of target tissues to thyroid hormone. Patients with thyroid hormone resistance have elevated free triiodothyronine (fT3) and/or free thyroxine (fT4) with inappropriately normal or elevated thyroid stimulating hormone (TSH). It is a diagnosis to consider in newborns presenting with abnormal thyroid function....

Resistance to thyroid hormone (RTH) is a genetic disorder characterized by reduced tissue responsiveness to thyroid hormone. We herein describe a 60-year old man who presented with the clinical features of cardiomyopathy, diabetes mellitus and elevated thyroid hormones with unsuppressed thyroid stimulating hormone. A genetic analysis of thyroid hormone receptor (TR) revealed a missense mutation...

Unrecognized congenital hypothyroidism leads to mental retardation. Newborn screening and thyroid therapy started within 2 weeks of age can normalize cognitive development. The primary thyroid-stimulating hormone screening has become standard in many parts of the world. However, newborn thyroid screening is not yet universal in some countries. Initial dosage of 10 to 15 g/kg levothyroxine is re...