The toxicity mechanisms of mercury and tin organic derivatives are still under debate. Generally the presence of organic moieties in their molecules makes these compounds lipophilic and membrane active species. The recent results suggest that Hg and Sn compounds deplete HS-groups in proteins, glutathione and glutathione-dependent enzymatic systems; this process also results in the production of...

One little-known area of chemistry is the chemistry of heavy main-group p elements, mostly metals and semimetals, in negative oxidation states. While the chemistry of Sn2+ and Sn4+, for example, is very well studied and we all learn about it very early in our education, not many people are aware of the fact that tin atoms can accept electrons and exhibit completely different reactivity when neg...

Single-crystal X-ray diffraction structures of organotin compounds bearing hemicarbonate and carbonate ligands were recently reviewed by us—“CO2 Derivatives Molecular Tin Compounds. Part 1: Hemicarbonato Carbonato Complexes”, Inorganics 2020, 8, 31—based on crystallographic data available from the Cambridge Structural Database. Interestingly, this first collection revealed that most listed isol...

Simple and abundant carboxylic acids have been used as acyl radical precursor by means of visible-light photoredox catalysis. By the transient generation of a reactive anhydride intermediate, this redox-neutral approach offers a mild and rapid entry to high-value heterocyclic compounds without the need of UV irradiation, high temperature, high CO pressure, tin reagents, or peroxides.

Titanium chelate addition of aryl nucleophiles to cyclopropyl aldehyde 6 followed by a tin-catalyzed one-pot retro-aldol, acetalisation and lactonisation sequence afforded cis and trans γ-aryllactone acetals. A γ-furyllactone derived by this approach was further transformed in two steps to model compounds for the oxidised northeastern sectors of selected Pseudopterogorgia diterpenoids.

A facile synthesis of potential acetylcholinesterase (AChE) inhibitors, the tacrine analogues 3a-p, has been accomplished by direct cyclocondensation of 1-aryl-4-cyano-5-aminopyrazole with β-ketoesters using tin(IV) chloride as catalyst. The structures of all the compounds have been confirmed by IR, ¹H- and ¹³C-NMR.

Stannyloligosilanes, Preparation, Crystal Structure Stannyloligosilanes 1 and 2 with terminal organotin groups are available by reacting alkali metal trior diorganostannides with a,-dichloroor difluorosilanes, or by treatm ent of organochlorostannanes with a,a»-difluorosilanes in the presence o f m agnesium . A ttem pts to functionalize the triorganotin derivatives 2 by halogenation reagents...