AIM The objective of the present study was to analyse the causes behind reperforation of the tympanic membrane in the patients presenting with chronic otitis media (mesotympanitis) after type I--III intrameatal tympanoplasty. Characteristic of the patients and methods of investigation. Intrameatal type I--III tympanoplasty with the use of autotransplants was performed in 652 patients presenting...

OBJECTIVE To report a novel tympanoplasty modification for anterior tympanic membrane perforation closure. MATERIALS AND METHODS A prospective study on 13 patients who underwent inferior tympanoplasty between December 2008 and May 2011 was carried out. In our technique, an inferior rather than a posterior flap is raised and the graft is laid from the inferior direction to obtain better access...

We would like to address the manuscript entitled “Effects of Cell-Based Therapy for Treating Tympanic Membrane Perforations in Mice,” by Goncalves et al. The authors suggested that topical application of bone marrow–derived exogenous mesenchymal stem cells enhanced the healing of tympanic membrane perforations (TMPs) in the mice animal model of acute TMPs and could be a promising alternative to...

INTRODUCTION Promising treatments for tympanic membrane perforation closure have been studied. Therapies derived from tissue engineering probably eliminate the need for conventional surgery. Bacterial cellulose is presented as an alternative that is safe, biocompatible, and has low toxicity. OBJECTIVES To investigate the effect on healing of direct application of a bacterial cellulose graft o...

Background: Chronic suppurative otitis media is one of the most common otological problems in developing countries. It affects all age groups. Type-1 tympanolpasty is simple repair of tympanic membrane. The objectives of this study were to describe the outcome of type-1 tympanoplasty in terms of graft take rate, hearing improvement and complications. Material & Methods: This quasi-experimental ...

Tympanic membrane is the partition between external ear and middle layer which a vital component of human ear. Neglected or maltreated earache, discharge trauma lead to perforation tympanic membrane. Tympanoplasty surgical procedure performed repair perforated membrane, with/without reconstruction ossicles, with aim preventing reinfection restoring hearing ability. Type 1 tympanoplasty simple c...

Background: Assisted reproductive techniques (ART) are used with increasing frequency worldwide. The present research was conducted to determine the effects of ART on hearing defects and ear abnormalities. Materials and Methods: In a descriptive, cross-sectional, non-randomized study, the status of hearing and ear abnormalities was assessed in 300 newborns conceived by ART at Royan Institute, T...

Given the frequent use of improvised explosive devices (IEDs) around the world, the study of traumatic blast injuries is of increasing interest. The ear is the most common organ affected by blast injury because it is the body's most sensitive pressure transducer. We fabricated a blast chamber to re-create blast profiles similar to that of IEDs and used it to develop a reproducible mouse model t...