background: with respect to physical relations in force and pressure, we hypothesized that the prevalence of traumatic tympanic membrane perforation in patients with a patulous eustachian tube is greater than normal, because in eustachian tube patency, the internal air pressure of the middle ear will not increase after compression, subsequent to trauma. therefore the force upon the tympanic mem...

Background: With respect to physical relations in force and pressure, we hypothesized that the prevalence of traumatic tympanic membrane perforation in patients with a patulous Eustachian tube is greater than normal, because in Eustachian tube patency, the internal air pressure of the middle ear will not increase after compression, subsequent to trauma. Therefore the force upon the tympanic...

which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Correspondence First of all, we would like to thank you for your interesting comments to our study. Our study was concerning to the application of synthetic bio-material patch. As your recommendation, natural healing rate of acute tympanic membrane perforati...

UNLABELLED The most common etiologies of tympanic membrane perforation are infections and trauma. OBJECTIVE The objective of the present study was to assess the healing of traumatic tympanic membrane perforation in rats. METHODS The tympanic membrane from male Wistar rats was perforated in the anterior and posterior portions to the handle of the malleus. Five tympanic membranes were evaluat...

OBJECTIVE The goal of this study was to evaluate the effects of perforation edge approximation and direct application of basic fibroblast growth factor (bFGF) each alone on the healing of large traumatic tympanic membrane perforations with inverted edges in humans. STUDY DESIGN Prospective, sequential allocation, three-armed, controlled clinical study. SETTING University-affiliated teaching...