resistance attributable to efflux has been reported in a number of gram-negative species, including Salmonella and Pseudomonas. Strains expressing efflux mechanisms leading to fluoroquinolone resistance are cross-resistant to a number of structurally unrelated antimicrobial agents, permitting multidrug resistance to develop (6). Therefore, inhibition of efflux systems as targets of therapeutic ...

Received 30 January 2008; accepted 30 January 2008; electronically published 24 March 2008. Reprints or correspondence: Dr. John R. Wingard, 1376 Mowry Rd., Ste. 145, PO Box 103633, Gainesville, FL 326103633 ([email protected]). Clinical Infectious Diseases 2008; 46:1434–5 2008 by the Infectious Diseases Society of America. All rights reserved. 1058-4838/2008/4609-0017$15.00 DOI: 10.1086...

Biopsy reports from 150 periradicular tissue specimens obtained from teeth refractory to nonsurgical endodontic therapy were reviewed. The specimens were submitted by postdoctoral dental students in the Department of Endodontics, and the biopsy reports were prepared by oral pathologists at the University of Texas Health Science Center at San Antonio. The study found that 59.3% of the periradicu...

Recent findings in the domain of combining classifiers provide a surprising revision of the usefulness of diversity for modelling combined performance. Although there is a common agreement that a successful fusion system should be composed of accurate and diverse classifiers, experimental results show very weak correlations between various diversity measures and combining methods. Effectively n...