conclusions several adverse effects are associated to anti-hcv drugs, hence appropriate skin care management and follow-up are very important. a careful anamnesis before the initiation of triple therapy is necessary to identify previous dermatological diseases that could increase skin adverse effects incidence. case presentation we report a case of a patient who discontinued telaprevir because ...

BACKGROUND Dual antiplatelet therapy is usually superior to mono therapy in preventing recurrent vascular events (VEs). This systematic review assesses the safety and efficacy of triple antiplatelet therapy in comparison with dual therapy in reducing recurrent vascular events. METHODS Completed randomized controlled trials investigating the effect of triple versus dual antiplatelet therapy in...

OBJECTIVE There has been a marked decrease in the eradication rates of Helicobacter pylori infection with standard triple therapy worldwide. Hence, sequential therapy has gained attention as a promising treatment during the last few years. This study was carried out to compare the efficacy of sequential versus standard triple therapy in the context of clarithromycin (CLA) resistance. MATERIAL...

helicobacter pylori infection is a prevalent disease among iranian children. the purpose of this study was to compare the effect of ciprofloxacin and furazolidone on eradicating helicobacter pylori in iranian children in combination with amoxicillin and omeprazole. in this cohort study, helicobacter pylori infection was confirmed by gastroscopy, rapid urease test or pathologic assessments. a to...

during a period of 10 months from may to february 1995, 120 children (72 girls, 48 boys) with an age range of 4-16 years (mean age 10.87, s.d.±2.7) with chronic abdominal pain who had an abnormal endoscopy (gastroduodenal mucosal defect) and positive urease test were treated for h. pylori. patients were treated randomly with either metronidazole and amoxicillin (double therapy, group a) or metr...

A retrospective study was carried out in 110 cadaveric kidney transplant recipients to compare the effects of low doses of cyclosporine (CsA), azathioprine (AZP) and steroids (triple-drug therapy) with those of higher doses of steroids plus AZP (conventional immunosuppression). Graft survival rate in the triple-drug therapy was 77%, 69%, and 69% at 1, 3, and 5 years, respectively. This was sign...

BETWEEN September 10, 1995, and September 20, 1997, a total of 208 adult patients undergoing their first or second cadaveric renal transplantation alone were randomized to receive tacrolimus!prednisone (n = 106) or tacrolimus/prednisone/mycophenolate mofetil (n = 102), without induction antilymphocyte antibody therapy. The mean recipient age was 50.8 ::!:: 13.7 years (range 19 to 84). Thirty-on...

Standard triple therapy consisting of a proton pump inhibitor, amoxicillin and clarithromycin has occupied centre stage in the treatment of H pylori infection for many years and is endorsed by the most recent Asia Pacific consensus guidelines. Although there have been reports of significantly reduced efficacy in many parts of the world, the conventional wisdom in Malaysia is that standard tripl...

BACKGROUND/AIMS Trends in successful eradication of Helicobacter pylori using first-line triple therapy, consisting of a proton pump inhibitor, amoxicillin, and clarithromycin, have been understudied. We evaluated H. pylori eradication rates at a single center over the last 10 years and identified risk factors related to eradication failure. METHODS This study included 1,413 patients who were...