Background: Infection caused by Neisseria Gonorrhoeae increases the risk of pelvic inflammatory disease (PID). Gonococcal PID tends to be clinically more severe than non-gonococcal ones. The main is present two cases gonococcal PID, with rapid clinical and analytic progression, leading sepsis, but without imaging manifestations. Clinical presentation: 1. 41-year-old patient replacement intraute...

BACKGROUND Acidform gel, an acid-buffering product that inactivates spermatozoa, may be an effective topical non-hormonal contraceptive. This study was designed to evaluate the safety of vaginal dosing and effects of Acidform on mucosal immune mediators, antimicrobial properties of genital secretions, and vaginal microbiota. METHODS Thirty-six sexually abstinent U.S. women were randomized to ...

OBJECTIVE To confirm the safety of a new experimental Tampax tampon and applicator compared with that of a currently marketed Tampax tampon and applicator using comprehensive gynecological and microbiological assessments. METHODS A 2-month, single-blind, randomized, crossover study was conducted in which each subject served as her own control. Safety was evaluated by comparing potential produ...

Vaginitis is one of the commonest reproductive tract infections in sexually active women. In the present study clinicoetiological characterization of infectious vaginitis amongst 380 women of reproductive age group (18-45 years) was done. Bacterial vaginosis (BV) was detected by Nugent's scoring, Candida infection by culture, and trichomoniasis (TV) by wet mount. One hundred and ten (28.9%) wom...

Present research is about the In-situ gels for site specific delivery. In the present work, formulations with chitosan, bioadhesive and permeation enhancer and gellan gum ion activable gelling polymer and temperature sensitive polymeric systems was used for In-situ geliling. The developed formulations was characterized for various in-vitro parameters e.g. clarity, pH, isotonicity, viscosity, dr...

Case report-Subjects-Three cases are described oflong-standing vaginal candidosis due to Candida glabrata. These had failed to respond to local and systemic antifungals. In each case the infecting strain appeared resistant to a range of azole drugs in vitro. Clinical course-Case one-This patient recovered following prolonged treatment with oral itraconazole in combination with oral and vaginal ...