نتایج جستجو برای: 17 involved in angiogenesis
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Background and purpose: Endometriosis is a benign disorder defined by the presence of endometrial tissue out of pelvic cavity and is related to debilitating pelvic pain and infertility. MiRNAs, are a cluster of small endogenous noncoding RNA that bind to 3׳ UTR of target mRNA and cause mRNA degradation or repressing translation of mRNA. Mir-126 is a type of miRNA that is involved in many vital ...
Autophagy, the major lysosomal pathway for degradation and recycling of cytoplasmic materials, is increasingly recognized as a player in endothelial cell (EC) biology vascular pathology. Particularly solid tumors, tumor microenvironmental stress such hypoxia, nutrient deprivation, inflammatory mediators, metabolic aberrations stimulates autophagy tumor-associated blood vessels. Increased ECs ma...
background : angiogenesis, the formation of new blood vessels from preexisting ones, is among the most important physiological and pathological processes that occur in the body. under pathological conditions such as tumor growth, psoriasis, corneal neovascularization and rheumatoid arthritis, angiogenesis is substantial for the development of the disease. zataria multiflora is a member of the l...
BACKGROUND Angiogenesis has been shown to be a critical aspect of tumor growth and progression. Vascular endothelial growth factor (VEGF) has potent angiogenic activity and has been identified in a wide variety of malignancies, including pancreatic carcinoma. The tumor-suppressor gene p53 has been thought to regulate VEGF in angiogenesis. The aim of the current study was conducted to investigat...
Cerebral blood flow (CBF) is disrupted after focal ischemia in rats. We examined long-term hemodynamic and cerebrovascular changes in the rat thalamus after focal cerebral ischemia. Cerebral blood flow quantified by arterial spin labeling magnetic resonance imaging was decreased in the ipsilateral and contralateral thalamus 2 days after cerebral ischemia. Partial thalamic CBF recovery occurred ...
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