Vitamin D, discovered nearly a century ago, still receives intensive attention worldwide. In The Lancet today, Thomas Wang and colleagues, through a monumental eff ort by a large consortium of experts (the SUNLIGHT consortium), provide new data that help to explain the large variability of vitamin D status, as revealed by serum concentrations of 25-hydroxyvitamin D. Vitamin D defi ciency, even ...

A 42-d trial was conducted to study the influence of 2 plant extracts on performance, digestibility, and digestive organ weights in broilers. The feeding program consisted of a starter diet until 21 d and a finisher diet until 42 d. There were 4 treatment groups: control; 10 ppm avilamycin (AB); 200 ppm essential oil extract (EOE) from oregano, cinnamon, and pepper; and 5,000 ppm Labiatae extra...

BACKGROUND The role of dairy calcium intake and serum vitamin D concentrations in weight loss is controversial. OBJECTIVE The objective was to assess the association of dairy calcium intake and serum vitamin D with weight loss. DESIGN We analyzed data from participants in the 2-y Dietary Intervention Randomized Controlled Trial (DIRECT) [n = 322; mean body mass index (BMI; in kg/m²): 31; me...

PURPOSE More time outdoors is associated with a lesser risk of myopia, but the underlying mechanism is unclear. We tested the hypothesis that 25-hydroxyvitamin D (vitamin D) mediates the protective effects of time outdoors against myopia. METHODS We analyzed data for children participating in the Avon Longitudinal Study of Parents and Children (ALSPAC) population-based birth cohort: noncyclop...

BACKGROUND Vitamin D insufficiency is associated with suboptimal health. The prevalence of vitamin D insufficiency may be rising, but population-based trends are uncertain. We sought to evaluate US population trends in vitamin D insufficiency. METHODS We compared serum 25-hydroxyvitamin D (25[OH]D) levels from the Third National Health and Nutrition Examination Survey (NHANES III), collected ...

Introduction: D-galactose (D-gal) is well known as an appropriate agent to induced aging effects in the in vivo and in vitro models. In the present study, we selected crocin, the main constituent of Crocus sativus L. (Saffron), against D-gal cytotoxicity in human neuroblastoma SH-SY5Y cells. Materials and Methods:  Cells were pretreated with crocin (25-500 µM) for 24 h and then expos...