Renal cell carcinoma (RCC) is the most common malignant tumour of adult kidney (Eble et al., 2004), and RCC’s histopathology is subdivided into various categories, which clear cell renal cell carcinoma (ccRCC) is the most common pathological category, accounting for 70-80% of all RCCs (Young et al., 2001; Matsuura et al., 2011). In the last decades, there have been immense improvements in the t...

abstract the prerequisite for continuous organizational change in today’s dynamic and ever changing environments is the presence of intuitive, strategic or in a more clear sense, transformational leaders. because of increasing attention to the leadership factor in creating organizational evolution, and leaders’ role in organizational learning, this research attempts to examine the relationship ...

S imple biominerals are composed of complex structures, which often have precise architectural order over several length scales. TIlis amazing architecture contributes to their superior strength and toughness, allowing them to outperform synthetic materials. Biominerals rely heavily on their biological constituents, such as biomacromolecules, for' regulation of mineralization. Pathological mine...

eye lens is composed of cells of only one type — lens fibre cells — which derive from a monolayer of undifferentiated epithelial cells covering the anterior surface of the lens. In the bulk of the lens, these cells are arranged in concentric sheets, much like the layers of an onion. In order to minimise light scatter in the lens, the fibre cells have to be precisely aligned. The scanning electr...

Renal clear cell carcinoma (CCRCC) is an aggressive tumor for which new prognostic factors are needed. It has been suggested that CCRCCs co-expressing P53 and MDM2 could represent a special subgroup; therefore the aim of this study was to explore their immunohistochemical features. The material studied consisted of 470 cases of CCRCC. Immunohistochemistry for MDM2, P53, Ki-67, VEGF-A, VEGF-C, V...