OBJECTIVE To determine the feasibility of a PCR based strategy for prenatal diagnosis of Haemophilia-A in Pakistani Families. DESIGN Prospective. SETTING Department of Haematology, Armed Forces Institute of Pathology, Rawalpindi. SUBJECTS Five families with at least one child affected with Haemophilia-A. Each family comprised of father, mother, affected child and fetus when present. MAI...

This article is a comparative study of similar experiences in the American short story collection, Fire and Forget: Short Stories from the Long War edited by Roy Scranton and Matt Ghalagher and the Persian short story collection, A Vital Killing by Ahmad Dehghan as they belong to two different languages, different cultures, and different worldviews. It is an exploration of an overwhelmed psycho...

Carbohydrate-protein interactions are involved in a multitude of biological recognition processes. Since individual protein-carbohydrate interactions are usually weak, multivalency is often required to achieve biologically relevant binding affinities and selectivities. Among the possible mechanisms responsible for binding enhancement by multivalency, the simultaneous attachment of a multivalent...

The present study investigated the relationship between objective temperature and subjective temperature preferences in predicting performance in simple and complex cognitive tasks. We assessed the impact of room temperature (warm and cold) on the ability to "update" (and monitor) working memory (WM) representations in two groups of participants, who differed in their subjective temperature pre...

We analyze the structural design and the dynamical properties of a protein kinase network derived from the Transpath database. We consider structural properties, such as feedback cycles, pathway lengths, fraction of shortest pathways and crosstalk. Dynamic characteristics of the network are analyzed by using nonlinear differential equations with a special focus on kinase amplitudes and signal p...

Let Σ be a compact surface, and letM be a path metric space with π1(M) ∼= π1(Σ) and with the universal cover M̃ Gromov hyperbolic. We show that, under certain assumptions, the shortest realisation in M of a multicurve Σ can be approximated by a train track in M . In the case where M is a hyperbolic 3-manifold, this is well known (see for example [Bon]). The main result is stated as Theorem 0.1 h...

Sheko is African taurine cattle, valued for its milk yield, adaptation to humid tsetse infested environment and trypanotolerance. We used 30 microsatellite markers in analyzing 30 DNA samples. We found high genetic diversity and no genetic bottlenecks in endangered Sheko cattle. Sheko cattle have not undergone recent genetic bottlenecks, in spite of drastic reduction in its overall demographic ...

Allele frequency distributions of nine short tandem repeat (STR) loci, D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D7S820, and D13S317, HLA-DQA1 and polymarker (PM) loci were studied in a sample population from Sultanate of Oman, Middle East. Blood samples were collected from 162 unrelated individuals. For all STR, HLA-DQA1 and PM loci, no deviations from Hardy-Weinberg equilibrium, bas...

We introduce and study the concept of $alpha $-semi short modules.Using this concept we extend some of the basic results of $alpha $-short modules to $alpha $-semi short modules.We observe that if $M$ is an $alpha $-semi short module then the dual perfect dimension of $M$ is $alpha $ or $alpha +1$.%In particular, if a semiprime ring $R$ is $alpha $-semi short as an $R$-module, then its Noetheri...

background: the aim of the study was to assess the effect of four repeated ejaculations on the same day at two-hour intervals on conventional and functional semen parameters. methods: three healthy men (32±3.6 years) donated the first semen samples after 3-4 days of sexual abstinence followed by three subsequent samples on the same day at two-hour interval each. semen samples were processed and...