نتایج جستجو برای: ada2

تعداد نتایج: 189  

Journal: :Annals of the Rheumatic Diseases 2022

Background Adenosine Deaminase 2 Deficiency (DADA2) and Haploinsufficiency of A20 (HA20) are two recently described monogenic autoinflammatory diseases (AID). The uncontrolled inflammatory response has been associated with an increased risk AA amyloidosis in other AID, but there only reported patients DADA2-related so far. 1,2 Objectives We herein report a patient AID both DADA2 HA20. Methods u...

طویلانی , حیدر , عبدی , محمد , نادی , ابراهیم , کریمی , مهرداد, گودرزی, محمد تقی ,

چکیده زمینه و هدف: بیماری انسدادی مزمن ریه COPD (Chronic Obstructive Pulmonary Disease) بوسیله سازمان جهانی GOLD (Global Initiative For COPD) به عنوان بیماری تعریف شده است که با محدودیت جریان هوا مشخص می‌شود که بطور کامل برگشت‌پذیر نیست. COPD یکی از زیر مجموعه‌های بیماری‌های انسدادی ریه می‌باشد که فیبروز سیستیک، برونشیت و آسم را نیز در بر می‌گیرد. آنزیم ADA به شماره (E.C.3.5.4.4) باعث تبدیل آد...

Journal: :Clinical biochemistry 2009
Pegah Poursharifi Reza Saghiri Mina Ebrahimi-Rad Habibollah Nazem Zahra Pourpak Mostafa Moin Sedigheh Shams

OBJECTIVES We aimed to investigate the activity of ADA and its isoenzymes in serum of patients with various primary immunodeficiency (PID) syndromes. DESIGN AND METHODS Total ADA (tADA) and its isoenzymes were measured in 76 children with PID syndromes and 30 healthy controls using the Ellis method. RESULTS Our results indicated that tADA and ADA2 levels were higher in patients with Chronic...

Journal: :Annals of human genetics 1977
C Satoh R E Ferrell R J Tanis N Ueda S Kishimoto J V Neel H B Hamilton K Baba

Five enzyme systems, PGM1, PGM2, ADA, 6-PGD and AK, were examined by electrophoresis in over 4000 samples from Hiroshima and Nagasaki for the frequencies of common and rare variants. In the PGM1 system, the PGM2(1) allele and PGM7(1) allele were found in polymorphic proportions, In addition, five kinds of slow variants and three types of fast variants of PGM1 were detected. The PGM3(1)NGS1 alle...

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