AIMS Alcohol can directly impair protein synthesis in cultured myocytes as well as in in situ perfused skeletal muscle. However, alcohol in the general circulation diffuses rapidly into the central nervous system (CNS). Therefore, this study determined whether localized elevation of alcohol within the CNS is capable of decreasing muscle protein synthesis. METHODS Conscious unstrained male rat...

In 2010, NIAAA marked a significant milestone, celebrating 40 years of research on alcohol abuse and alcoholism. Throughout this time, NIAAA’s journal has played an important role, raising awareness about topics in alcohol research and ensuring that important findings from the field were disseminated to the widest possible audience. The journal began under the title Alcohol World. It had a news...

INTRODUCTION Drug abuse is a social, moral, and penal problem in Poland since many years. Ethyl alcohol remains the prime cause of concern. The effect of narcotics (including alcohol) on trauma has been the object of investigations for years. STUDY OBJECTIVES 1) To determine the reliability of subjective assessment of sobriety of the patient by the physician. 2) To determine correlations betw...

The rheological response of blends obtained from quaternized polysulfone and polyvinyl alcohol in N-methyl-2pyrrolidone as against structural peculiarity of polymers from the blend, composition of polymer mixtures, as well as the types of interactions were investigated. Results show that the variation of polyvinyl alcohol composition in the studied system determines changes of the rheological p...

background: this review was performed to evaluate the trend of alcohol use, characteristics of consumers, alcohol use disorders and toxic alcohol intoxications in bangladesh. in addition, sources and sales figures of alcoholic beverages, and number of legal permits issued for alcohol consumption are reported and analyzed. methods: a narrative search was performed on available medical literature...

The effect of prolonged administration of alcohol on calcium binding and uptake by sarcoplasmic reticulum and mitochondria and on respiratory function of mitochondria was investigated in heart muscle of dogs. Dogs were paired and maintained with and without alcohol for 6 months; alcohol was administered by adding it to drinking water and food with vitamin supplements. Measurements were made aft...

The thermal denaturation of lysozyme in aqueous alcohol solutions has been investigated through ultraviolet difference spectrophotometry and optical rotation measurements. Alcohols used were CH30H, C2H50H, and C3H70H; concentrations up to 50% (v/v) of alcohol in water were employed. It was found that upon increasing the size or the concentration of the aliphatic alcohol, the denaturation temper...

For decades, compounds present in foods and beverages have been implicated in the etiology of human cancers. The World Health Organization (WHO) International Agency for Research on Cancer (IARC) continues to classify such agents regarding their potential carcinogenicity in humans based on new evidence from animal and human studies. Furfuryl alcohol and β-myrcene are potential human carcinogens...

Long-term ethanol exposure leads to a sexually dimorphic response in both the susceptibility to cardiac pathology (protective effect of the female heart) and the expression of selected myocardial proteins. The purpose of the present study was to use proteomics to examine the effect of chronic alcohol consumption on a broader array of cardiac proteins and how these were affected between the sexe...