BACKGROUND Allergic Rhinitis is a common Ear, Nose and Throat disorder. Asthma and Allergic Rhinitis are diseases with similar underlying mechanism and pathogenesis. The aim of this survey was to highlight current treatment trends for Allergic Rhinitis and Asthma. METHOD A questionnaire was emailed to all registered consultant members of the British Association of Otorhinolaryngologists - Hea...

BACKGROUND A T helper cell (TH) 17-biased response has been observed in patients with allergic asthma, particularly in those with neutrophil accumulation in the lung. Therefore, we sought to test the hypothesis that neutrophils might be an important source of interleukin (IL)-17 in allergic asthma. METHODS Whole peripheral blood cells from non-asthmatic control subjects (n = 17) and patients ...

PURPOSE Allergic disease and its comorbidities significantly influence the quality of life. Although the comorbidities of allergic diseases are well described in adult populations, little is known about them in preschool children. In the present study, we aimed to assess the prevalence and comorbidity of allergic diseases in Korean preschool children. METHODS We conducted a cross-sectional st...

19 cats were nper-sensitized to allergic asthma by receiving a concomitant spray ang injection of ovalbumin (10% fresh egg-white in normal saline) every other days for four weeks.then animals were anesthetized and left femoral artery cannulation performed to record atrerial pressure and take blood samples.left femoral vein was cannulated to infuse nutritional fluids and grugs as needed.trachea ...

Background Subcutaneous allergen-specific immunotherapy (SCIT) is a valuable treatment option for patients with controlled mild to moderate allergic asthma However, SCIT is contraindicated for patients with severe persistent asthma due to a potential systemic allergic reaction. Several studies in adolescents and adults with persistent allergic rhinitis and moderate persistent allergic asthma ha...

BACKGROUND/AIM Asthma is one of the most common chronic pulmonary diseases. The number of asthmatics has been continuously increasing all over the world. Depending on its causing agent, asthma is classified as allergic and nonallergic. Asthma is often associated with other allergic diseases, and it is most commonly preceded by the symptoms of rhinitis. The aim of this study was to establish the...

Asthma is a chronic inflammatory airways disease that usually begins in early life and involves gene-environment interactions. Although most asthma exhibits allergic inflammation, many allergic individuals do not have asthma. Here, we report how the asthma gene a disintegrin and metalloprotease 33 (ADAM33) acts as local tissue susceptibility gene that promotes allergic asthma. We show that enzy...

BACKGROUND Patients with allergic rhinitis and allergic asthma demonstrate comparable local and systemic eosinophil inflammation, and yet they present with different clinical pictures. Less is even known about the contribution of neutrophil inflammation in allergic diseases. The aim of the study was to examine the propensity and selectivity of granule release from primed systemic eosinophils an...

allergic rhinitis and asthma share common  epidemiological features and inflammatory processes. the aim of the present study was to document the influence of natural allergen exposure in exhaled no  (eno)  and in spirometric parameters of patients with seasonal allergic rhinitis(sar) and to investigate the differences among subjects with positive versus negative bronchial provocation to metacho...