During alcoholic fermentation, the yeasts responsible for process produce various metabolites, including urea. The reaction of urea with ethanol spontaneously generates ethyl carbamate in wine, a carcinogenic metabolite whose concentration needs to be regulated. Yeasts during arginine metabolic pathway. For this purpose, adaptive evolution has been used by using toxic analogue l-arginine, l-can...

The different combinations of bioactive compounds, probiotics (Streptococcus thermophilus ATCC 19258 and Lactobacillus bulgaricus BAA-2844), prebiotic (fructooligosaccharides, FOS), fenugreek, L-arginine, were added to the pâtė meat. Some meats contaminated with Salmonella Typhimurium 14028 Listeria monocytogenes 7644. Fermentation was applied only batches containing ‘probiotic’ or ‘probiotic p...

Abstract AIMS Glioblastoma is a primary brain malignancy with poor prognosis. The immunosuppressive microenvironment, molecular heterogeneity and the blood-brain barrier makes this tumour diffcult to treat. Targeted immune therapies have shown limited success, highlighting need for novel therapies. We previously demonstrated effectiveness of arginine deprivation using ADI-PEG20 when combined ra...

Changes in extra and intracellular neurotransmitter amino acids concentration in the early stage of acute cerebral ischemia have been reported. In this the study, serum level of gamma aminobutyric acid (GABA) and L-Arginine in acute ischemic stroke patients was assessed. 60 patients with acute ischemic stroke and sixthy healthy volunteers as a control group were assessed. Serum GABA was measure...

Heavy metals pollution is one of the key environmental problems. In this research, the effect of seed priming with salicylic acid and sodium hydrosulfide was investigated on methionine and arginine amino acids contents and some compounds derived from their metabolism as well as ZmACS6 and ZmSAMD transcripts levels in maize plants under lead stress. For this purpose, maize seeds were soaked in s...

introduction: the mechanisms of hepatic encephalopathy are not fully understood. moreover, there is no comprehensive data concerning the effects of nitric oxide (no) system on anxiolytic-like behaviors induced by bile duct ligation (bdl). methods: male mice weighing 25-30 g were used and anxiety-like behaviors were tested using hole-board task. results: the data indicated that cholestasis incre...