BACKGROUND Recently, we found that Staphylococcus aureus produces extracellular vesicles (EV) that contain pathogenic proteins. Although S. aureus infection has been linked with atopic dermatitis (AD), the identities of the causative agents from S. aureus are controversial. We evaluated whether S. aureus-derived EV are causally related to the pathogenesis of AD. METHODS Extracellular vesicles...

Staphylococcus aureus is an opportunistic pathogen and variable component of the human microbiota. A characteristic of atopic eczema (AE) is colonization by S. aureus, with exacerbations associated with an increased bacterial burden of the organism. Despite this, the origins and genetic diversity of S. aureus colonizing individual patients during AE disease flares is poorly understood. To exami...

background and objective: vancomycin is frequently the antibiotic of choice for the treatment of infections caused by methicillin-resistant staphylococcus aureus (mrsa). for the last years, the incidence of vancomycin-intermediate s. aureus (visa) and vancomycin-resistant s. aureus (vrsa) has been increased in various parts of the world. the present study was carried out to determine the presen...

conclusions the present study reports on a high rate of multi-drug resistance, the predominance of the frequency of class 1 integron, and the emergence of spa type t790 among iranian staphylococcus aureus strains. the results revealed that the dissemination of multi-drug resistance among staphylococcus aureus isolates may be associated with the presence of integrons. therefore, continuous surve...

conclusion: the outcome of this study show that spa and coa typing are suitable meth­ods for mrsa isolates typing because it is easy to use and interpret them, and that these methods can be useful in infection source detection and its control especially in epidemic situations. result: pcr results showed seven different patterns for staff and five different patterns for patients based on spa gen...

conclusions the remarkable rates of biofilm production ability among clinically isolated staphylococci emphasize the necessity of more effective infections control policies to prevent biofilm formation on medical devices and hospital environmental surfaces. background biofilm formation capacity is recognized as an important virulence factor in staphylococci that makes the organisms more resista...

background: staphylococcus aureus is a major human pathogen. due to high prevalence of s. aureus infections and increasing resistance to antibiotics, physicians have been facing problems in choosing the appropriate empirical antibiotic therapy for such infections. objectives: the aim of this study was to determine the pattern of antibiotic resistance in s. aureus clinical isolates of mashhad qu...

staphylococcus aureus is a major bacterial pathogen that causes different community- and hospital-acquired infections. over time, strains of s. aureus have become resistant to different antibiotics including penicillinase-resistant penicillins. having data on the local antimicrobial susceptibility pattern of this pathogen is necessary for selection of appropriate antibiotics for empirical treat...

background and objectives: staphylococcal food poisoning is a gastrointestinal disease, which is caused by consumption of contaminated food with enterotoxins produced by staphylococcus aureus (ses). milk and its products are known sources of food borne diseases. this study was carried out to evaluate the prevalence of enterotoxigenic s. aureus strains in organic milk and cheese in tabriz - iran...

INTRODUCTION Reintroduction of endangered animals as part of conservational programs bears the risk of importing human pathogens from the sanctuary to the natural habitat. One bacterial pathogen that serves as a model organism to analyze this transmission is Staphylococcus aureus as it can colonize and infect both humans and animals. The aim of this study was to evaluate the utility of various ...