conclusions resistance to oxacillin and other antibiotics was high, and most of the isolates were found to be multi-drug resistance (mdr). plasmid analysis of representative s. aureus isolates also demonstrates the presence of a wide range of plasmid sizes, with no consistent relationship between plasmid profiles and resistance phenotypes. regular surveillance of hospital infections and monitor...

background protein a is the virulence factors of staphylococcus aureus rolling in its pathogenesis, and its gene is used for typing. polymerase chain reaction-restriction fragment length polymorphism (pcr-rflp) with different enzymes has been used for this action. objectives in this study, we used bsp143i enzyme for digestion of the gene, coding protein a (spa gene) in s. aureus. the bacteria w...

conclusions in the present study, we found a high prevalence of mrsa at the hospitals studied. the findings emphasized the increased prevalence of mrsa isolates containing different toxin and adhesion genes, probably accompanied by antimicrobial resistance. infection with such isolates worsens the clinical outcomes as well as the morbidity and mortality rates in hospitalized patients in icus. m...

introduction: one of the most important agents in hospital-acquired infections is staphylococcus aureus. treatment of methicillin-resistant s. aureus (mrsa) infections with decreased susceptibility to vancomycin has recently been more difficult. the aim of this study was to evaluate the possible presence of vancomycin intermediate s. aureus (visa) and vancomycin- resistant s. aureus (vrsa) and ...

staphylococcus aureus causes a wide variety of infections worldwide. methicillin-resistant s. aureus is one of most common causes of nosocomial and community acquired infections. the fluoroquinolones are an important class of antibiotics that used to treat infections caused by s. aureus. today, a significant increase in the rate of ciprofloxacin resistance in methicillin-resistant s. aureus str...

abstract        background and objective: staphylococcus aureus is the most common and important infectious agent. this bacterium can enter the bloodstream and cause some complications in the intensive care unit (icu).this organism can frequently be found in the nose and transmitted by the carriers. this study aimed to determine the efficiency of eradicating s. aureus from the nose of icu perso...

Intravascular infection due to Staphylococcus aureus requires colonization of subendothelium in the presence of shear forces. von Willebrand factor (VWF) is a large multimeric glycoprotein playing a key role in platelet adhesion to subendothelium. To determine whether VWF may also play a role in adhesion of S. aureus to endovascular sites, binding of VWF to S. aureus and adhesion of S. aureus t...

tigecycline is a new glycylcycline antibiotic structurally similar to minocycline antibiotic. it has broad spectrum activity, including staphylococcus aureus infections. this is the first study that evaluated the activity of tigecycline against staphylococcus aureus isolated from biological samples in iran. in vitro activity of tigecycline against 160 staphylococcus aureus including 99 methicil...