To the Editor: Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA), which carries genes for Panton-Valentine leukocidin (PVL), has become a major concern worldwide (1–3). CA-MRSA is mainly associated with skin and soft tissue infections in young, otherwise healthy, persons in the community (3) and also with life-threatening sepsis and community-acquired pneumonia (preceded ...

Cytotoxic chemotherapy has shown little antitumor activity against renal cell carcinoma (RCC). It has been demonstrated that RCC cells secrete interleukin 6 (1L-6) and express II.-6 receptors (11,-oKs). IL-6 inhibits apoptosis and enhances manganese Superoxide dismutase expres sion. Several anticancer chemotherapeutic agents exert their cytotoxic activity in part through the induction of apopto...

in this paper, a new spectral-iterative method is employed to give approximate solutions of fractional logistic differential equation. this approach is based on combination of two different methods, i.e. the iterative method cite{35} and the spectral method. the method reduces the differential equation to systems of linear algebraic equations and then the resulting systems are solved by a numer...

Sir Essential tremor is usually considered to be a monosymptomatic disorder with variable clinical expression, about half of all cases demonstrating an autosomal dominant pattern of inheritance.' Possible associations with other movement disorders have been described, including Parkinson's disease.2 We report a patient with hereditary essential tremor and the restless legs syndrome. A 71-year-o...

I t is axiomatic that resuscitation begins with airway stabilization. Recognition of the need to intubate may seem straightforward compared with the task of selecting which agent(s) to give, and at what dose, at a time when seconds count. Each sedative agent has its strengths and weaknesses, and a distinct dose–response curve. The choice of agents is made more difficult by the complexity of res...

Comment The toxic shock syndrome was first reported in seven children in 19782; in five of these Staphylococcus aureus was isolated from various sites. The occurrence of toxic shock syndrome in menstruating women was first reported in 19803; since then 299 cases have been reported in the United States with 25 deaths.4 About 95, of these cases have occurred in menstruating women, all of whom had...

Acetylsalicylk acid (ASA) is known to prevent cancer development, but its mechanism of action remains unclear. In this study, we compared the efficacies of this nonspecific cyclooxygenase (COX) inhibitor with N-[2(cyclohexyloxy)-4-nitrophenyl]-methanesulfonamide (NS-398), a specific COX-2 inhibitor. COX-2-specific inhibitors are less toxic than ASA. Lung tumorigenesis was induced in A/J mice by...

ratings of different diagnostic groups yielded no significant differences except that "being in hospital" was more highly regarded by those with alcohol or drug dependence, manic patients rating this as the least helpful (one way analysis of variance; df= 6; F = 2 224; p<O005). Comment Ironically this study shows that the thing psychiatric inpatients value most about being in hospital is their ...