نتایج جستجو برای: binding domain

تعداد نتایج: 761113  

Journal: :Social Science Research Network 2021

Filopodia assemble unique integrin-adhesion complexes to sense the extracellular matrix. However, mechanisms of integrin localization and regulation in filopodia are poorly defined. Here, we observed that active integrins accumulate at tip myosin-X(MYO10)-positive while inactive uniformly distributed. RNAi depletion 10 activity modulators identified talin as principal activator filopodia. Delet...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه شیراز - دانشکده علوم 1390

throughout this dissertation r is a commutative ring with identity and m is a unitary r-module. in this dissertation we investigate submodules of multiplication , prufer and dedekind modules. we also stat the equivalent conditions for which is ring , wher l is a submodule of afaithful multiplication prufer module. we introduce the concept of integrally closed modules and show that faithful mu...

Abstract It was shown that several pathogenic bacterial effector proteins contain the Glu-Pro-Ile-Tyr-Ala (EPIYA) or a similar sequence. These bacterial EPIYA effectors are delivered into host cell via type III or IV secretion system, where they undergo tyrosine phosphorylation at the EPIYA sequences, which triggers interaction with multiple host cell SH2 domain-containing proteins and thereby...

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