We studied 91 offspring of ABO incompatible preganacies and 30 controls resulting from O--O pregnancies to test whether cord bilirubin levels could be used to predict the severity of hyperbilirubinaemia in ABO incompatibility. Blood group, direct Coombs's test, and serum bilirubin estimations were carried out on cord blood, and bilirubin estimations at 12, 24, 36, and 48 hours of life.

BACKGROUND AND OBJECTIVES Blood incompatibility arises from individual and ethnic differences in red blood cell (RBC) antigen profiles. This underlines the importance of documenting RBC antigen variability in various ethnic groups. Central Asia is an area with a long and complex migratory history. The purpose of this article is to describe key antigen frequencies of Afghan ethnic groups in the ...

Background: Neonatal jaundice is a common problem that can result in serious neurological side effect such as Kern icterus. Several drugs are used to prevent neonatal jaundice. The effect of clofibrate in the prevention of hyperbilirubi-nemia in healthy term neonates has not been paid attention to. This study aimed to evaluate the preventive effect of clofibrate on neonatal jaundice in ter...

With data on 91 alloimmunized thrombocytopenic patients and 389 donor-recipient pairs matched or selectively mismatched for HLA antigens, it was observed that ABO incompatibility significantly reduced the effectiveness of platelet transfusions. The mean 24-hr recovery of platelets from histocompatible donors and from donors selectively mismatched for cross-reactive HLA antigens was decreased by...

OBJECTIVE Uncross-matched blood either group specific or Group O is advocated in patients with exsanguinating haemorrhage when cross-matched blood cannot be made available rapidly. The risk of using uncross-matched blood is not known clearly. The purpose of this study is to attempt to quantify the risk of major transfusion reactions resulting from the use of uncross-matched group specific blood...

Since its discovery, it had been generally considered that blood type was hereditarily neutral characteristics free from natural selection. Thereafter many observations were reported on the correlations between blood types and hemolytic diseases in newborn or erythroblastosis foetalis and differential survival in intrauterine life such as rate of fertility and of miscarriage and in extra-uterin...

Phenobarbitone acts as an inducer of hepatic enzymes resulting in accelerated uptake, conjugation and excretion of bilirubin.'> Its prophylactic use in a high risk setting such as ABO incompatibility may help in reducing the need for phototherapy and exchange transfusions. From May to December 1998, a prospective study was done at the Neonatal Intensive Care Unit, St John's Medical College and ...