Platelet rich plasma (PRP) is an autologous source of growth factors. By application of PRP around cementless implants alone or in combination with bone allograft chips, early implant fixation and gap healing could be improved. We inserted two porous HA coated titanium implants extraarticularly in each proximal humerus of eight dogs. Each implant was surrounded by a 2.5 mm gap. Four treatments ...

Cartilage and bone degradation, observed in human rheumatoid arthritis (RA), are caused by aberrant expression of proteinases, resulting in an imbalance of these degrading enzymes and their inhibitors. However, the role of the individual proteinases in the pathogenesis of degradation is not yet completely understood. Murine antigen-induced arthritis (AIA) is a well-established animal model of R...

Enchondroma of the hand is a common lesion with a recurrence rate of up to 13.3% after curettage and bone grafting. Pathologic fractures often occur. Although allograft bone chips are widely used in the surgical treatment of enchondroma, the use of structural allograft bone has not been reported before. This case report presents a recurrent enchondroma of the fifth metacarpal with pathologic fr...

Background: Given the popularity of pterional craniotomy, numerous modifications have been made to prevent postoperative deformities. With advent titanium plates, fixation has become both simple and excellent. However, plates can cause skin problems, infection, or skull growth fail. Methods: To develop a simple, cost-effective, esthetically satisfactory method, without use non-metallic material...

Orthopaedic surgical cutting instruments are required to generate sufficient forces penetrate bone tissue while minimising the risk of thermal and mechanical damage surrounding environment. This study presents a combined experimental–computational approach determine relationships between key parameters overall performance polyurethane-based synthetic trabecular analogue under orthogonal conditi...