a functional treatment for skeletal damages in orthopedic and oral maxillofacial surgeries is required. platelet growth factors such as platelet derived growth factor (pdgf), bone morphogenic factor (bmp), transferring growth factor-β (tgf-β) and insulin-like growth factor-1 (igf-1) proceed wound healing and bone regeneration. in the present study we focused on the effect of platelet rich plasm...

AIM To evaluate histologically the morphology and characteristics of bone chips harvested intraorally by Safescraper, a specially designed cortical bone collector. MATERIAL AND METHODS Bone chips harvested near a bone defect or in other intraoral sites were grafted into a post-extractive socket or applied in procedures for maxillary sinus floor augmentation or guided bone regeneration. Core b...

Background and Aim: Implant site preparation with minimal trauma is an important factor in success of implant treatment and has a great effect on osseointegration. Piezoelectric bone surgery was introduced as a modern technique for micrometric osteotomy with precise, controllable action. Preservation of osteoblast cell viability is critical to achieve successful osseointegration. The present st...

BACKGROUND Allograft bone used in joint replacement surgery can additionally serve as a carrier for antibiotics and serve as a prophylaxis against infections. However, in vitro dose-response curves for bone chips impregnated with different kinds of antibiotics are not available. In addition, while it would be desirable to add the antibiotics to allograft bone chips before these are stored in a ...

This study aimed to develop a new biodegradable polymeric cage to convert corticocancellous bone chips into a structured strut graft for treating segmental bone defects. A total of 24 adult New Zealand white rabbits underwent a left femoral segmental bone defect creation. Twelve rabbits in group A underwent three-dimensional (3D) printed cage insertion, corticocancellous chips implantation, and...

BACKGROUND studies in humans and animals have shown that following tooth removal (loss), the alveolar ridge becomes markedly reduced. Attempts made to counteract such ridge diminution by installing implants in the fresh extraction sockets were not successful, while socket grafting with anorganic bovine bone mineral prevented ridge contraction. AIM to examine whether grafting of the alveolar s...

BACKGROUND This study was undertaken to assess the radiologic outcome of spinal fusion, with bone chips from laminectomy in patients with lumbar spondylolisthesis. METHODS From January 1993 to September 2001, 95 patients with lumbar spondylolisthesis were managed and followed up well at our Orthopedic Division. All patients presented with persistent low back pain, radiculopathy and claudicati...

The aim of this work was to compare the osteogenicity of calcium phosphate ceramic granules with autologous bone graft in ectopic and orthotopic sites. Biphasic calcium phosphate (BCP) granules composed of hydroxyapatite (HA) and beta-tricalcium phosphate (beta-TCP) in a 60/40 ratio were sintered at 1050, 1125 and 1200 degrees C, producing different microporosities. Either BCP ceramic granules ...