A 44 years old male patient had suffered extensive 3rd degree burns on both legs, undergoing thorough surgical debridement, resulting in both tibias being exposed. Approximately 5 months after the incident he was referred to the Department of Plastic and Reconstructive Surgery of the University Hospital Gent, Belgium, to undergo flap reconstruction. Free flap surgery was performed twice on both...

INTRODUCTION The rationale for operative treatment of depressed tibial plateau fractures is anatomic reduction, stable fixation and grafting. Grafting options include autogenous bone graft or bone substitutes. METHODS The autograft group included 18 patients with depressed tibial plateau fractures treated with autogenous bone grafting from the ipsilateral femoral condyle following open reduct...

Under physiological conditions bone defects often occur at mechanical load bearing sites and bone substitutes used for regeneration should be similarly subjected to mechanical loading stress. In this study, we investigated whether a novel heel-strike like mechanical loading method can be used as a complementary therapy to promote bone regeneration following bone substitute grafting. To test thi...

OBJECTIVES To evaluate whether the adjunctive use of a bone substitute at immediate single implants placed in fresh extraction sockets with a residual buccal bone-to-implant gap of at least 1 mm could improve the aesthetic outcome of guided bone regeneration (GBR). MATERIALS AND METHODS Eighty patients requiring bone augmentation at a single immediate postextractive implant to improve the aes...

Bone fracture healing is a complex process including inflammation, repair and remodeling. Bone grafts or substitute are widely accepted to treat impaired healing. Newly developed bone substitutes must undergo in vitro and in vivo testing before clinical application. All kinds of intraosseous and heterotopic implant models in small and/ or large animals are used for different bone substitutes. O...

This reviews objective is to inform readers of a creative substitute for traditional drilling techniques that keeps host bone in the greatest possible biological shape implant placement. 4 Optic and electronic microscopy have also demonstrated obtained through this method live bone. crucial since clinical studies indicated autogenous best filler defects. gathering may make it easier manipulate ...

normal 0 false false false en-us x-none ar-sa unicameral bone cysts (ubcs) are benign, osteolytic lesions which are often asymptomatic and are commonly seen in the proximal of humerus and femur. the average age at diagnosis is 9-11 years and there is a male preponderance with a male-to-female ratio of approximately 2-2.5 to 1. we describe a case of 5-year-old girl who presented to orthopedic cl...

PURPOSE The aim of this study was to determine whether biphasic calcium phosphate (BCP) bone substitute with two different concentrations of Escherichia coli-expressed recombinant human bone morphogenetic protein 2 (ErhBMP-2) enhances new bone formation in a standardized rabbit sinus model and to evaluate the concentration-dependent effect of ErhBMP-2. METHODS Standardized, 6-mm diameter defe...

BACKGROUND Many (artificial) bone substitute materials are currently available for use in orthopaedic trauma surgery. Objective data on their biological and biomechanical characteristics, which determine their clinical application, is mostly lacking. The aim of this study was to investigate structural and in vitro mechanical properties of nine bone substitute cements registered for use in ortho...