UNLABELLED In addition to their well characterized and established role in haemostasis and thrombosis, platelets contribute to the pathogenesis of inflammation. Adenine nucleotides are signalling molecules that regulate the function of virtually every cell in the body, by interacting with P2 receptors. Their important role in inflammation is well established. In the last few years, the pro-infl...

Background: Analog radiography has been replaced with digital radiography for canine diagnostic imaging in many veterinary clinics. There is no data comparing these modalities in a veterinary clinical setting to detect bronchial pattern signs in dogs. Objectives: In this study, computerized digital radiography (CR) and analog radiography were compared for diagnosis of bronchial pattern in dogs....

introduction: to assess the efficacy and safety of bronchial artery embolization in the treatment of massive hemoptysis.   materials and methods: a retrospective study on 46 patients (26 males and 20 females) who were referred to the razavi hospital from april 2009 to may 2012 with massive hemoptysis and had bronchial artery embolization procedures. general characteristics of the patients inclu...

BACKGROUND Mould exposure has been linked to childhood asthma and bronchial hyper-responsiveness. Few studies have assessed beta-(1,3)-d-glucan (beta-glucan), a significant fungal cell wall constituent, in relation to asthma in adolescence. OBJECTIVE To determine whether house dust-derived beta-glucan exposure at age 7-10 is associated with the development and persistence of atopic and non-at...

BACKGROUND It has been proposed that T helper (Th)2-driven immune deviation in early life can be countered by Th1 inducing childhood infections and that such counter-regulation can protect against allergic asthma. OBJECTIVE To test whether Th1-inducing infection with Bordetella pertussis protects against allergic asthma using well-characterized murine models. METHODS Groups of mice were sen...

BACKGROUND Although asthma is strongly associated with immediate hypersensitivity to indoor allergens, several studies have suggested that a cat in the house can decrease the risk of asthma. We investigated the immune response to cat and mite allergens, and asthma among children with a wide range of allergen exposure. METHODS We did a population-based cross-sectional study of children (aged 1...

As a potent bronchodilator, the anti-inflammatory effects of tiotropium and its interaction with budesonide against cadmium-induced acute pulmonary inflammation were investigated. Compared to values obtained in rats exposed to cadmium, cytological analysis indicated a significant decrease of total cell and neutrophil counts and protein concentration in bronchoalveolar lavage fluid (BALF) in rat...