We report a series of four cases presented with transient ischemic attacks (TIA) or ischemic stroke as the predominant manifestation of neurobrucellosis (NB). Three of the patients were 20-28 years of age, and one patient was 53 years old. They all used to consume unpasteurized milk or its products. Two patients had systemic brucellosis in the past and received antibiotic treatment. Other cause...

Brucellosis is a world-wide zoonosis and systemic disease affecting various organs. The causative organism is an intracellular proteobacteria gram-negative bacillus of the genus Brucella. Human brucellosis is a multi organ disease, transmitted via unpasteurized animal milk and cheese. A renewed scientific interest in human brucellosis has be enfueled by its recent reemergence [1,2]. Symptoms ar...

Arctic foxes (Vulpes lagopus) are susceptible to smooth Brucella (s-Brucella) infection and may be exposed such bacteria through the consumption of infected marine mammals, as implied by finding s-Brucella antibodies in polar bears (Ursus maritimus). Svalbard have not previously been investigated for s-Brucella antibodies, but antibodies detected Iceland, Alaska (USA) Russia...

Abstract Brucella spp. are facultative intracellular bacterial pathogens that have the ability to survive and multiply in professional nonprofessional phagocytes. Successful invasion chronic persistence indicate manipulates various host cellular processes create a replication permissive niche. The essential mechanisms factors support of remain poorly understood. RNA interference (RNAi) is poten...

Endocarditis is rarely reported in sheep and information presented for ovine endocarditis is based mostly on comparative findings in the cattle. Infective vegetative endocarditis of the right heart was diagnosed in a 3-year-old fat-tailed ram. Clinical findings included tachycardia, marked brisket edema, jugular veins distention and pulsation and pale mucous membranes. Hematologic abnormality i...

Multilocus enzyme electrophoresis (MLEE) of 99 Brucella isolates, including the type strains from all recognized species, revealed a very limited genetic diversity and supports the proposal of a monospecific genus. In MLEE-derived dendrograms, Brucella abortus and a marine Brucella sp. grouped into a single electrophoretic type related to Brucella neotomae and Brucella ovis. Brucella suis and B...

With the aim of developing quantitative PCR methods for the detection and differentiation of Brucella species, the genomes of Brucella ceti, Brucella inopinata, Brucella netotomae, and Brucella suis biovar 4 were sequenced and analyzed.