OBJECTIVE Our aim was to ascertain the effect of an infection control program, using education and performance feedback on intensive care units, for intravascular device (IVD)-associated bloodstream infection (BSI). METHODS Within 4 level III, adult, intensive care units in Argentina, all admitted, adult patients with a central vascular catheter in place for at least 24 hours were included. T...

OBJECTIVES Asthmatics have increased risks of airway-related infections. Little is known about whether this is true for non-airway-related serious infections such as Escherichia coli bloodstream infection (BSI). We assessed whether asthma is associated with a risk of developing community-acquired E coli BSI. DESIGN The study was designed as a population-based retrospective case-control study....

UNLABELLED BACKGROUND The objective of this study was to explore the prognostic value of the Bone Scan Index (BSI) obtained at the time of diagnosis in a group of high-risk prostate cancer patients receiving primary hormonal therapy. METHODS This was a retrospective study based on 130 consecutive prostate cancer patients at high risk, based on clinical stage (T2c/T3/T4), Gleason score (8 t...

Biological uptake of dissolved silicate (DSi) and formation of biogenic silica (BSi) during diatom growth modifies the form of Si carried from the continents to the world ocean. Significant concentrations of BSi, averaging 28.0 pmol L-l, are found in all sizes of rivers. The global contribution of BSi carried by rivers was estimated as 1.05 ? 0.20 Tmol Si year’. Combined with the global mean ri...

BACKGROUND Gram-negative bacterial bloodstream infection (BSI) is a serious condition with estimated 30% mortality. Clinical outcomes for patients with severe infections improve when antibiotics are appropriately chosen and given early. The objective of this study was to estimate the association of prior healthcare exposure on time to appropriate antibiotic therapy in patients with gram-negativ...

BACKGROUND The occurrence of bloodstream infection (BSI) and antimicrobial resistance have been increasing in many countries. We studied trends in antimicrobial resistance and empiric antibiotic therapy at a medium-sized general hospital in Mid-Norway. METHODS Between 2002 and 2013, 1995 prospectively recorded episodes of BSI in 1719 patients aged 16-99 years were included. We analyzed the an...

UNLABELLED A reproducible and quantitative imaging biomarker is needed to standardize the evaluation of changes in bone scans of prostate cancer patients with skeletal metastasis. We performed a series of analytic validation studies to evaluate the performance of the automated bone scan index (BSI) as an imaging biomarker in patients with metastatic prostate cancer. METHODS Three separate ana...

Bloodstream infections (BSI) and Clostridium difficile infections (CDI) in pediatric oncology/hematology/bone marrow transplant (BMT) populations are associated with significant morbidity and mortality. The objective of this study was to explore possible associations between altered microbiome composition and the occurrence of BSI and CDI in a cohort of pediatric oncology patients. Stool sample...

Biogenic silica (BSi) contents in the marsh plants (Phragmites australis, Scirpus mariqueter and Spartina alterniflora) and associated sediments in Chongming Island eastern intertidal flat of the Yangtze Estuary were determined. The BSi contents in P. australis, S. mariqueter and S. alterniflora varied from 25.78-42.74 mg/g, 5.71-19.53 mg/g and 6.71-8.92 mg/g, respectively. Over the entire grow...

Infection control personnel familiar with the studies underlying recent guideline recommendations for the prevention of intravascular catheter-related infections could conclude that it would be easy to minimize the risk of such infections. Randomized, controlled trials have demonstrated that prepping the skin with chlorhexidine antiseptic can reduce the risk of catheter-related bloodstream infe...