Cisplatin is a common chemotherapeutic agent that used for treatment of many solid cancers. Rapid identification of chemotherapy resistance is very important and may lead to effective treatment plan. Spectroscopy techniques, such as infrared spectroscopy, which are sensitive to biochemical composition of samples, have shown potentials to discriminate tissues. Developing in Fourier transform inf...

tumor growth is characterized by uncontrolled cell division. for centuries, silver kushta powder, composed of nano and submicro silver particles, has been used in traditional iranian and pakistani medicine for the treatment of melanoma and breast cancer. we have found that these nanocomposite particles are similar to silver nanoparticles (agnps) in size and shape and that there are so differenc...

Different types of Artemisia aucheri extracts were reported to have various biological activities including a cytotoxic effect on some cancer cell lines. We investigated the antiproliferative activity of isolated sesquiterpenoids from petroleum ether extract of Artemisia aucheri (A. aucheri)aerial parts on SK-N-MC, MCF-7, and A2780 cell lines. Phytochemicals from the petroleum ether cold macera...

introduction: human calprotectin is an abundant protein in the neutrophil, monocyte and macrophage cytosol. effect of proliferation inhibition of this protein has been elucidated on hepatoma, melanoma, murine fibrosarcoma lukemia and human adenocarcenoma breast cancer but not in human gastric cancer cell lines. in present study, in vitro proliferation inhibition effect of calprotectin in differ...

Background and objectives: Natural products are one of the major sources for investigations of novel medicines. Zataria multiflora Boiss (ZM) has shown pharmacological activities especially in gastrointestinal tract; however, there are limited studies about its cytotoxicity effects. In this study, the effect of Zataria multiflora was examined on two colon canc...

methanolic extract of 15 iranian medicinal plants were prepared and tested for their cytotoxic activities against three cancer cell lines (mcf7, hepg2 , wehi164) and one normal cell line (mdbk). some plants showed cytotoxic activities. the extract of ferula szowitsiana root, which proved to be the most active, was chosen for further phytochemical studies. the major compounds of the most potent ...

background: the metabolically active tumor cells may be characterized by a pronounced adenosine release that regulates the growth and development of the tumor. consequently, the expression pattern of defined receptor subtypes will be an important determinant for specific effects of adenosine on the control of tumor cell growth. in recent studies, the expression profile, signal transduction, mol...