Abstract Designing a feasible in vitro enzyme cascade is challenging task that often preceded by optimization steps. Computational methods can increase the efficiency of process providing deeper insight into system. In this study, bottlenecks farnesyl pyrophosphate‐producing were determined combination silico modeling and wet‐lab experiments. ATP precursor‐isomerizing isopentenyl diphosphate δ ...

a simple semi-phenomenological model, which accurately predicts the dependence of thresholdcurrent for temperature of resonant-phonon three well quantum cascade laser based on verticaltransitions is offered. we found that, the longitude optical phonon scattering of thermally excitedelectrons is the most important limiting factor for thermal performance of high frequency thz qcls.in low frequenc...

We describe a MIX cascade protocol and a reputation system that together increase the reliability of a network of MIX cascades. In our protocol, MIX nodes periodically generate a communally random seed that, along with their reputations, determines cascade configuration. Nodes send test messages to monitor their cascades. Senders can also demonstrate message decryptions to convince honest casca...

There has been significant increase in penetration of renewable generation (RG) sources all over the world. Localized concentration of many such generators could initiate a cascade tripping sequence that might threaten the stability of the entire system. Understanding the impact of cascade tripping process would help the system planner identify trip sequences that must be blocked in order to in...