abstract background: although studies have demonstrated significant negative relationships between quality of life (qol), fatigue, and the most common psychological symptoms (depression, anxiety, stress), the main ambiguity of previous studies on qol is in the relative importance of these predictors. also, there is lack of adequate knowledge about the actual contribution of each of them in the ...

multiple sclerosis (ms) is a chronic disease of central nervous system. the multiple sclerosis information system (msis), such as other information system (is), depends on identification, collection and processing of data for producing useful information. lack of the integrated is for collecting standard data causes undesirable effects on exchanging, comparing, and managing. the aim of this stu...

A large number of research groups have proposed that chronic fatigue syndrome (CFS), fibromyalgia (FM), multiple chemical sensitivity (MCS) and, in some cases, posttraumatic stress disorder (PTSD) have multiple overlaps and may share a common etiology (cause). They have: • overlapping symptoms • many people are diagnosed as having more than one • cases of each are commonly initiated by a short ...

Stress activates multiple neural and endocrine systems to allow an animal to respond to and survive in a threatening environment. The corticotropin-releasing factor system is a primary initiator of this integrated response, which includes activation of the sympathetic nervous system and the hypothalamic-pituitary-adrenal (HPA) axis. The energetic response to acute stress is determined by the na...

Plants have evolved adaptive mechanisms that allow them to tolerate a continuous range of abiotic and biotic stressors. Tropospheric ozone (O3), a global anthropogenic pollutant, directly affects living organisms and ecosystems, including plant-herbivore interactions. In this study, we investigate the stress responses of Brassica nigra (wild black mustard) exposed consecutively to O3 and the sp...

Introduction: Certain types of chronic mental stress impair memory. On the other hand, crocin is introduced in the medical literature as an effective component of saffron with remedial effects on memory impairment. This study investigated the effects of crocin on spatial and cognitive memories, locomotor activity, novel recognition conditions and serum corticosterone levels in rats under chroni...

BACKGROUND We used diffusion-tensor cardiac MR to investigate myocardial microstructure changes, including tissue integrity (mean diffusivity [MD], fractional anisotropy) and fiber architecture (helix angles) in patients with recent myocardial infarction (MI). This study aimed to investigate the sequential changes of myocardial microstructure and its relationships with changes of macrostructure...

Chronic stress is known to precipitate and exacerbate neuropsychiatric symptoms, and exposure to stress is particularly pathological in individuals with certain genetic predispositions. Recent genome wide association studies have identified single nucleotide polymorphisms (SNPs) in the gene CACNA1C, which codes for the Cav1.2 subunit of the L-type calcium channel (LTCC), as a common risk varian...

OBJECTIVE The aim of this two-year prospective study was to examine the relationship between multiple aspects of life-event stress and relapse in multiple sclerosis (MS) patients. BACKGROUND Few studies have defined the critical features of this life-event stress; for example, stressor duration, frequency, severity, disease-dependency, valency, or stressor constructs, such as the propensity t...