نتایج جستجو برای: closed in vitro dissolution test method

تعداد نتایج: 17333692  

Journal: :iranian journal of pharmaceutical research 0
alen shahbazian department of medicinal chemistry, pharmaceutical sciences branch, islamic azad university, tehran, iran. asghar davood department of medicinal chemistry, pharmaceutical sciences branch, islamic azad university, tehran, iran alireza dabirsiaghi department of pharmaceutical sciences, pharmaceutical sciences branch, islamic azad university, tehran, iran.

piroxicam has two different crystalline forms (known as needle and cubic forms), that they are different in physicochemical properties such as biological solubility. in the current research, using taguchi experimental design approach the influences of five operating variables on formation of the piroxicam polymorph shapes in recrystallization were studied. the variables include type of solvent,...

2013
SAKINA FATIMA SHAHNAZ USMAN IYAD NAEEM MUHAMMAD

Objective: Simvastatin is lipid lowering agent that reduces the risk of total mortality and morbidity. For such a sensitive medicine, the availability of un-control brands, local and multinational is a point of thought. The objective of this study was to provide a comparative assessment of dissolution profile of six different brands of Simvastatin by applying dissolution profile comparison appr...

2013
J. Sruti Ch. N. Patra S. K. Swain S. Beg H. R. Palatasingh S. C. Dinda M. E. Bhanoji Rao

A combination of fusion and surface adsorption techniques was used to enhance the dissolution rate of cefuroxime axetil. Solid dispersions of cefuroxime axetil were prepared by two methods, namely fusion method using poloxamer 188 alone and combination of poloxamer 188 and Neusilin US2 by fusion and surface adsorption method. Solid dispersions were evaluated for solubility, phase solubility, fl...

2007
F. A. Chaibva

The objective of these studies was to develop a discriminatory in vitro release test for assessing formulation factors that may affect oxytocin (OT) release during formulation development studies of a Pluronic® F127 OT in situ gel-forming parenteral dosage form. An appropriate release assessment method should be able to discriminate between the performance of different formulation compositions ...

Journal: :physiology and pharmacology 0
valiollah hajhashemi dept. pharmacology and isfahan pharmaceutical research center, school of pharmacy, isfahan univ. med. sci., isfahan. mohsen minaiyan mahdi saberian-boroojeni

introduction: urine morphine test, in several countries is the most primarily available qualitative test for detecting opioid abusers. since the users of illicit drugs attempt to defeat urine tests and there are also plenty of claims that usage of hd (high dose) contraceptive pills can result in false-negative results, we decided to design the present study to investigate the probable in vitro ...

2016
Ragna Berthelsen René Holm Jette Jacobsen Jakob Kristensen Bertil Abrahamsson Anette Müllertz

This study describes various complications related to sample preparation (filtration) during development of a dissolution method intended to discriminate among different fenofibrate immediate-release formulations. Several dissolution apparatus and sample preparation techniques were tested. The flow-through cell apparatus (USP 4) was found unfit for dissolution testing of fenofibrate MeltDose fo...

2015

European Journal of Pharmaceutical Sciences 13 2001 123133 www.elsevier.nllocateejps. Modeling and comparison of dissolution profiles.To compare dissolution profiles between two drug products model dependent curve fitting, statistic analysis and model independent methods can be used. To compare dissolution profiles between two drug products model dependent curve fitting, statistic analysis and ...

Journal: :Journal of chromatographic science 2007
Saleem Shaikh M S Muneera O A Thusleem Muhammad Tahir Anand V Kondaguli K Ruckmani

A new specific, accurate, precise, and reproducible selective online dissolution method for rosiglitazone maleate is developed and validated for the dissolution of rosiglitazone maleate in pharmaceutical formulations. The rationale of the method is based on the direct measurement of the absorbance of the analyte in the buffer medium at 242 nm using buffer as blank. Dissolution is achieved on a ...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه علامه طباطبایی 1389

this study was an attempt to investigate the effect of using c-test passages on the reading comprehension and incidental vocabulary learning of iranian intermediate efl learners. the participants were 60 male efl learners at kish mehr institute in garmsar. in fact, there were two groups, an experimental group and a comparison group with 30 students in each. the participants were pretested throu...

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