Neonatal hearing loss is the most frequent sensorial congenital defect in newborns. No data are available on worldwide prevalence of congenital deafness. World Health Organization (WHO) data indicate 1-4 cases per 1000 individuals, with a considerable increase in developing countries. A prevalence exceeding 1 per 1000 however, indicates a serious public health problem calling for urgent attenti...

Consanguineous marriages are practiced worldwide but very common as social characteristic norms of the tribal society Pakistan and have reached (~63%). Couples married within blood relatives, inheriting different genetic disorders including epilepsy in their offspring.
 Objectives: The present work is ever first attempt to reaffirm association between disease (ED) consanguinity Tribal Soci...

Populations in heterotic equilibrium show a greater percentage decrease than populations in mutational equilibrium, but the difference is very small for rare genes. Mortality and morbidity data on inbred offspring from consanguineous marriages cannot distinguish genes in one type of equilibrium from those in another. The current concept of genetic load is based on artefacts rather than on inher...

Fertility rates in Pakistan have remained consistently high over the past three decades. While numerous studies have examined sociodemographic determinants, the role of biological factors, and particularly consanguinity, has received little attention, even though marriage between close biological relatives continues to be the norm in Pakistan. Reproductive behaviour among women in consanguineou...

Four children (two boys and two girls) with hypoparathyroidism, renal insufficiency, and developmental delay are described. They were the products of consanguineous marriages in three related Asian families presenting over a six year period. All the children died within the first 15 months of life despite treatment. Postmortem examination on one child showed absent parathyroid glands. We believ...

We report the first Brazilian family with Brown-Vialetto-van Laere syndrome. The presence of consanguineous marriages and illness affecting three sisters and one niece support an autosomal recessive transmission. The age at onset of the illness ranged from 12 to 20 years old. The time interval between hearing loss and involvement of other cranial nerves varied from 3 to 12 years. MRI demonstrat...

Background: The birth of a child with a hearing disability is a stressful event in the family. Since consanguineous marriages are associated with the incidence of congenital hearing loss, it is expected that such parents will experience greater psychological problems. Objective: The current study investigated and compared anxiety, depression, and stress i...

Purpose: This study exposes the rate of consanguineous marriages in afghan population and its effects on health their children.
 Methodology: A questionnaire was designed to collect data. total 2300 respondents were asked about socio-demographic attitude towards which 2201 responded according criteria. The paper describes quantitative qualitative types surveys, include field observations d...

Objectives: The prevalence of consanguineous marriage is about 30 % in Iran and this can increase the probability of incidence of genetic impairments such as hearing impairments. Hearing impairment in comparison with other hereditary disorders is the most incident. The purpose of this survey is to identify the prevalence of consanguinity among the parents of sensoryneural hearing impaired stude...